Diagnosis and Management of Bacterial Vaginosis and Other Types of Abnormal Vaginal Bacterial Flora: A Review

被引:70
作者
Donders, Gilbert [1 ]
机构
[1] Reg Hosp H Hart Tienen, Dept Obstet & Gynecol, Leuven, Belgium
关键词
PREVENT PRETERM DELIVERY; SEXUALLY-TRANSMITTED INFECTIONS; LACTOBACILLUS-RHAMNOSUS GR-1; GENITAL-TRACT INFECTION; ORAL METRONIDAZOLE; PREGNANT-WOMEN; RISK-FACTORS; GARDNERELLA-VAGINALIS; ANTIBIOTIC-TREATMENT; 1ST TRIMESTER;
D O I
10.1097/OGX.0b013e3181e09621
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Bacterial vaginosis (BV) is a common cause of abnormal vaginal discharge. It is characterised by an overgrowth of predominantly anaerobic organisms (Gardnerella vaginalis, Prevotella spp., Peptostreptocci, Mobiluncus spp.) in the vagina leading to a replacement of lactobacilli and an increase in vaginal pH. BV can arise and remit spontaneously, but often presents as a chronic or recurrent disease. BV is found most often in women of childbearing age, but may also be encountered in menopausal women, and is rather rare in children. The clinical and microscopic features and diagnosis of BV are herein reviewed, and antibiotic and non-antibiotic treatment approaches discussed. Target Audience: Obstetricians & Gynecologists, Family Physicians Learning Objectives: After completion of this educational activity, the participant should be better able to analyze bacterial vaginosis clinically, formulate an oral antibiotic treatment regimen for bacterial vaginosis and use vaginal treatments for bacterial vaginosis.
引用
收藏
页码:462 / 473
页数:12
相关论文
共 165 条
[1]   Prevalence of Candida albicans and bacterial vaginosis in asymptomatic pregnant women in South Yorkshire, United Kingdom [J].
Akinbiyi, A. A. ;
Watson, Robert ;
Feyi-Waboso, Paul .
ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2008, 278 (05) :463-466
[2]   CLINDAMYCIN VAGINAL CREAM VERSUS ORAL METRONIDAZOLE IN THE TREATMENT OF BACTERIAL VAGINOSIS - A PROSPECTIVE DOUBLE-BLIND CLINICAL-TRIAL [J].
ANDRES, FJ ;
PARKER, R ;
HOSEIN, I ;
BENRUBI, GI .
SOUTHERN MEDICAL JOURNAL, 1992, 85 (11) :1077-1080
[3]   Augmentation of antimicrobial metronidazole therapy of bacterial vaginosis with oral probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14:: randomized, double-blind, placebo controlled trial [J].
Anukam, Kingsley ;
Osazuwa, Emmanuel ;
Ahonkhai, Jeoma ;
Ngwu, Michael ;
Osemene, Gibson ;
Bruce, Andrew W. ;
Reid, Gregor .
MICROBES AND INFECTION, 2006, 8 (06) :1450-1454
[4]   Clinical study comparing probiotic Lactobacillus GR-1 and RC-14 with metronidazole vaginal gel to treat symptomatic bacterial vaginosis [J].
Anukam, Kingsley C. ;
Osazuwa, Emmanuel ;
Osemene, Gibson I. ;
Ehigiagbe, Felix ;
Bruce, Andrew W. ;
Reid, Gregor .
MICROBES AND INFECTION, 2006, 8 (12-13) :2772-2776
[5]   Bacterial vaginosis and HIV acquisition: a meta-analysis of published studies [J].
Atashili, Julius ;
Poole, Charles ;
Ndumbe, Peter M. ;
Adimora, Adaora A. ;
Smith, Jennifer S. .
AIDS, 2008, 22 (12) :1493-1501
[6]  
Audisio T, 2001, J Low Genit Tract Dis, V5, P223, DOI 10.1046/j.1526-0976.2001.54007.x
[7]   Microbiologic response to treatment of bacterial vaginosis with topical clindamycin or metronidazole [J].
Austin, MN ;
Beigi, RH ;
Meyn, LA ;
Hillier, SL .
JOURNAL OF CLINICAL MICROBIOLOGY, 2005, 43 (09) :4492-4497
[8]   Prospective study of correlates of vaginal Lactobacillus colonisation among high-risk HIV-1 seronegative women [J].
Baeten, J. M. ;
Hassan, W. M. ;
Chohan, V. ;
Richardson, B. A. ;
Mandaliya, K. ;
Ndinya-Achola, J. O. ;
Jaoko, W. ;
McClelland, R. S. .
SEXUALLY TRANSMITTED INFECTIONS, 2009, 85 (05) :348-353
[9]   Mobiluncus species in gynaecological and obstetric infections:: antimicrobial resistance and prevalence in a Turkish population [J].
Bahar, H ;
Torun, MM ;
Öçer, F ;
Kocazeybek, B .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2005, 25 (03) :268-271
[10]   Rate of preterm births in pregnant women with common lower genital tract infection: a population-based study based on the clinical practice [J].
Banhidy, Ferenc ;
Acs, Nandor ;
Puho, Erzsebet H. ;
Czeizel, Andrew E. .
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2009, 22 (05) :410-418