Defective ion channel function in the long QT syndrome: Multiple unexpected mechanisms

被引：5

作者：

Roden, DM ^{[1
]}

机构：

[1] Vanderbilt Univ, Sch Med, Div Clin Pharmacol, Nashville, TN 37232 USA

来源：

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY | 2001年 / 33卷 / 02期

关键词：

D O I：

10.1006/jmcc.2000.1323

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：185 / 187

页数：3

共 20 条

[1] MOLECULAR MECHANISM FOR AN INHERITED CARDIAC-ARRHYTHMIA [J].

BENNETT, PB ;

YAZAWA, K ;

MAKITA, N ;

GEORGE, AL .

NATURE, 1995, 376 (6542) :683-685

[2]

BLANCHI L, 2000, AM J PHYSIOL-HEART C, V279, pH3003

[3] Properties of KvLQT1 K+ channel mutations in Romano-Ward and Jervell and Lange-Nielsen inherited cardiac arrhythmias [J].

Chouabe, C ;

Neyroud, N ;

Guicheney, P ;

Lazdunski, M ;

Romey, G ;

Barhanin, J .

EMBO JOURNAL, 1997, 16 (17) :5472-5479

[4] Multiple mechanisms of Na+ channel-linked long-QT syndrome [J].

Dumaine, R ;

Wang, Q ;

Keating, MT ;

Hartmann, HA ;

Schwartz, PJ ;

Brown, AM ;

Kirsch, GE .

CIRCULATION RESEARCH, 1996, 78 (05) :916-924

[5] RESTORATION OF INACTIVATION AND BLOCK OF OPEN SODIUM-CHANNELS BY AN INACTIVATION GATE PEPTIDE [J].

EAHOLTZ, G ;

SCHEUER, T ;

CATTERALL, WA .

NEURON, 1994, 12 (05) :1041-1048

[6] Novel characteristics of a misprocessed mutant HERG channel linked to hereditary long QT syndrome [J].

Ficker, E ;

Thomas, D ;

Viswanathan, PC ;

Dennis, AT ;

Priori, SG ;

Napolitano, C ;

Memmi, M ;

Wible, BA ;

Kaufman, ES ;

Iyengar, S ;

Schwartz, PJ ;

Rudy, Y ;

Brown, AM .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2000, 279 (04) :H1748-H1756

[7] Novel gain-of-function mechanism in K+ channel-related Long-QT syndrome:: Altered gating and selectivity in the HERG1 N629D mutant [J].

Lees-Miller, JP ;

Duan, YJ ;

Teng, GQ ;

Thorstad, K ;

Duff, HJ .

CIRCULATION RESEARCH, 2000, 86 (05) :507-513

[8] Age- and sex-related differences in clinical manifestations in patients with congenital long-QT syndrome - Findings from the international LQTS registry [J].

Locati, EH ;

Zareba, W ;

Moss, AJ ;

Schwartz, PJ ;

Vincent, GM ;

Lehmann, MH ;

Towbin, JA ;

Priori, SG ;

Napolitano, C ;

Robinson, JL ;

Andrews, M ;

Timothy, K ;

Hall, WJ .

CIRCULATION, 1998, 97 (22) :2237-2244

[9] Effectiveness and limitations of β-blocker therapy in congenital long-QT syndrome [J].

Moss, AJ ;

Zareba, W ;

Hall, WJ ;

Schwartz, PJ ;

Crampton, RS ;

Benhorin, J ;

Vincent, GM ;

Locati, EH ;

Priori, SG ;

Napolitano, C ;

Medina, A ;

Zhang, L ;

Robinson, JL ;

Timothy, K ;

Towbin, JA ;

Andrews, ML .

CIRCULATION, 2000, 101 (06) :616-623

[10] Low penetrance in the long-QT syndrome - Clinical impact [J].

Priori, SG ;

Napolitano, C ;

Schwartz, PJ .

CIRCULATION, 1999, 99 (04) :529-533

← 1 2 →