Modulation of cold pain in human brain by electric acupoint stimulation: evidence from fMRI

被引：83

作者：

Zhang, WT

Jin, Z

Huang, J

Zhang, L

Zeng, YW

Luo, F

Chen, ACN

Han, JS

机构：

[1] Peking Univ, Dept Neurobiol, Beijing 100083, Peoples R China

[2] Hosp 306, Dept Radiol, Beijing 100101, Peoples R China

[3] Hosp 306, fMRI Ctr, Beijing 100101, Peoples R China

[4] Aalborg Univ, Human Brain Mapping & Cort Imaging Lab, Aalborg, Denmark

来源：

NEUROREPORT | 2003年 / 14卷 / 12期

关键词：

acupuncture; analgesia; anterior cingulate cortex; fMRI; pain; somatosensory area;

D O I：

10.1097/00001756-200308260-00010

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

The purpose of this study is to investigate the modulation of pain responses in the human brain by electric acupoint stimulation (EAS). Eight healthy subjects were enrolled; each received real or mock EAS treatment in separate sessions. Cool (18degreesC) and cold (2degreesC) stimuli were delivered, during which functional magnetic resonance imaging scans were performed, before and after treatment. Real EAS specifically increased the pain-specific activation in bilateral secondary somatosensory area, medial prefrontal cortex, and Brodmann area (BA) 32, while it decreased the activation in contralateral primary somatosensory area, BA7, and BA24. We suggest that EAS may induce an analgesic effect via modulation of both the sensory and the emotional aspect of pain processing.

引用

页码：1591 / 1596

页数：6

共 24 条

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Acupuncture produces central activations in pain regions [J].