Secretion of milk proteins

被引：60

作者：

Burgoyne, RD ^{[1
]}

Duncan, JS ^{[1
]}

机构：

[1] Univ Liverpool, Physiol Lab, Liverpool L69 3BX, Merseyside, England

来源：

JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA | 1998年 / 3卷 / 03期

关键词：

mammary gland; lactation; secretion; exocytosis; transcytosis; vesicular traffic;

D O I：

10.1023/A:1018763427108

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mammary epithelial cells secrete milk proteins in a polarized manner from their apical surface during lactation. These secreted proteins are either synthesized by the mammary cells or are transported by transcytosis from blood plasma. The intracellular trafficking pathways by which milk proteins are secreted are known in general outline. In this review the basic cell biology of the mammary epithelial cell secretory pathway is considered in relation to what is known in more detail for other cell types. In addition, potential points of control of protein secretion are examined. The secretory biology of mammary epithelial cells has not been characterized extensively in recent years and, while some aspects are well understood, other key issues, which still remain to be resolved, have been highlighted.

引用

页码：275 / 286

页数：12

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