The evolution of self-tolerance: a new cell arises to meet the challenge of self-reactivity

被引：146

作者：

Fazekas de St Groth, B ^{[1
]}

机构：

[1] Centenary Inst Canc Med & Cell Biol, Washington, DC 20422 USA

来源：

IMMUNOLOGY TODAY | 1998年 / 19卷 / 10期

关键词：

D O I：

10.1016/S0167-5699(98)01328-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

yNaive T cells can become either tolerant or immune as a result of their first encounter with antigen. It has been suggested that lymphoid and myeloid dendritic cells, respectively control such decisions. Here, BArbara Fazekas de St Groth discusses evolutionary aspects of the functional distinction between these two types of dendritic cells.

引用

页码：448 / 454

页数：7

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