Differential cell death response to photodynamic therapy is dependent on dose and cell type

被引：115

作者：

Wyld, L ^{[1
]}

Reed, MWR ^{[1
]}

Brown, NJ ^{[1
]}

机构：

[1] Univ Sheffield, Royal Hallamshire Hosp, Div Clin Sci, Sect Surg & Anaesthet Sci, Sheffield S10 2JF, S Yorkshire, England

来源：

BRITISH JOURNAL OF CANCER | 2001年 / 84卷 / 10期

关键词：

D O I：

10.1054/bjoc.2001.1795

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

PDT-induced cell death. by either apoptosis or necrosis may vary with cell type or PDT dose. 5 cell types were treated with varying doses of aminolaevulinic acid-induced PDT and the type of cell death analysed. The mode of cell death was found to depend on both cell type and light dose. (C) 2001 Cancer Research Campaign.

引用

页码：1384 / 1386

页数：3

共 13 条

[1]

Bonsing BA, 1997, CYTOMETRY, V28, P11, DOI 10.1002/(SICI)1097-0320(19970501)28:1<11::AID-CYTO2>3.3.CO

[2]

2-H

[3]

COOPER MJ, 1994, ONCOL RES, V6, P569

[4]

CRISSMAN HA, 1995, CELL GROWTH APOPTOSI, P21

[5] IDENTIFICATION OF PROGRAMMED CELL-DEATH INSITU VIA SPECIFIC LABELING OF NUCLEAR-DNA FRAGMENTATION [J].

GAVRIELI, Y ;

SHERMAN, Y ;

BENSASSON, SA .

JOURNAL OF CELL BIOLOGY, 1992, 119 (03) :493-501

[6]

HEWETT PW, 1993, IN VITRO CELL DEV-AN, V29A, P823

[7] Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis [J].

Jänicke, RU ;

Sprengart, ML ;

Wati, MR ;

Porter, AG .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (16) :9357-9360

[8]

KESSEL D, 1995, P SOC PHOTO-OPT INS, V2392, P122, DOI 10.1117/12.208180

[9] Different apoptotic pathways are induced from various intracellular sites by tetraphenylporphyrins and light [J].

Noodt, BB ;

Berg, K ;

Stokke, T ;

Peng, Q ;

Nesland, JM .

BRITISH JOURNAL OF CANCER, 1999, 79 (01) :72-81

[10]

Sharma K, 1998, INT J CANCER, V76, P259, DOI 10.1002/(SICI)1097-0215(19980413)76:2<259::AID-IJC14>3.0.CO

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