Preparation of new trifluoromethyl substituted tri- and tetracyclic heterocycles with Peganin skeleton from a methyl 3,3,3-trifluoropyruvate 2-aminobenzylamine adduct

被引：13

作者：

Dolensky, B

Kvicala, J

Paleta, O

Cejka, J

Ondracek, J

机构：

[1] INST CHEM TECHNOL,DEPT ORGAN CHEM,PRAGUE 16628 6,CZECH REPUBLIC

[2] INST CHEM TECHNOL,DEPT SOLID STATE CHEM,PRAGUE 16628 6,CZECH REPUBLIC

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 38期

关键词：

D O I：

10.1016/0040-4039(96)01517-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of 2-aminobenzylamine to methyl trifluoropyruvate afforded methyl 2-((2-aminobenzyl)amino) -3.3,3-trifluoro-2-hydroxypropionate, which reacted with various ketones to give new fluorinated tricyclic and tetracyclic heterocycles with the skeleton of the alkaloid Peganin. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：6939 / 6942

页数：4

共 11 条

[1] INHIBITION OF EPSP SYNTHASE BY ANALOGS OF THE TETRAHEDRAL INTERMEDIATE AND OF EPSP [J].