Imatinib mesylate elicits positive clinical response in atypical chronic myeloid leukemia involving the platelet-derived growth factor receptor beta

被引：29

作者：

Garcia, JL ^{[1
]}

de Mora, JF ^{[1
]}

Hernandez, JM ^{[1
]}

Queizan, JA ^{[1
]}

Gutierrez, NC ^{[1
]}

Hernandez, JM ^{[1
]}

San Miguel, JF ^{[1
]}

机构：

[1] Hosp Univ Salamanca, Hematol Serv, Salamanca 37007, Spain

来源：

BLOOD | 2003年 / 102卷 / 07期

关键词：

D O I：

10.1182/blood-2003-05-1579

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2699 / 2700

页数：2

共 7 条

[1] Glivec (ST1571, Imatinib), a rationally developed, targeted anticancer drug [J].

Capdeville, R ;

Buchdunger, E ;

Zimmermann, J ;

Matter, A .

NATURE REVIEWS DRUG DISCOVERY, 2002, 1 (07) :493-502

[2] A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome [J].

Cools, J ;

DeAngelo, DJ ;

Gotlib, J ;

Stover, EH ;

Legare, RD ;

Cortes, J ;

Kutok, J ;

Clark, J ;

Galinsky, I ;

Griffin, JD ;

Cross, NCP ;

Tefferi, A ;

Malone, J ;

Alam, R ;

Schrier, SL ;

Schmid, J ;

Rose, M ;

Vandenberghe, P ;

Verhoef, G ;

Boogaerts, M ;

Wlodarska, I ;

Kantarjian, H ;

Marynen, P ;

Coutre, SE ;

Stone, R ;

Gilliland, DG .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (13) :1201-1214

[3] Clinical, hematological and cytogenetic characteristics of atypical chronic myeloid leukemia [J].

Hernández, JM ;

del Cañizo, MC ;

Cuneo, A ;

García, JL ;

Gutiérrez, NC ;

González, M ;

Castoldi, G ;

San Miguel, JF .

ANNALS OF ONCOLOGY, 2000, 11 (04) :441-444

[4]

Kulkarni S, 2000, CANCER RES, V60, P3592

[5] Activity of STI571 in chronic myelomonocytic leukemia with a platelet-derived growth factor β receptor fusion oncogene [J].

Magnusson, MK ;

Meade, KE ;

Nakamura, R ;

Barrett, J ;

Dunbar, CE .

BLOOD, 2002, 100 (03) :1088-1091

[6] Structural mechanism for STI-571 inhibition of Abelson tyrosine kinase [J].

Schindler, T ;

Bornmann, W ;

Pellicena, P ;

Miller, WT ;

Clarkson, B ;

Kuriyan, J .

SCIENCE, 2000, 289 (5486) :1938-1942

[7] H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor β gene in atypical chronic myeloid leukemia with t(5;10)(q33;q22) [J].

Schwaller, J ;

Anastasiadou, E ;

Cain, D ;

Kutok, J ;

Wojiski, S ;

Williams, IR ;

LaStarza, R ;

Crescenzi, B ;

Sternberg, DW ;

Andreasson, P ;

Schiavo, R ;

Siena, S ;

Mecucci, C ;

Gilliland, DG .

BLOOD, 2001, 97 (12) :3910-3918

← 1 →