Protofibrils, the unifying toxic molecule of neurodegenerative disorders?

被引:78
作者
Haass, C [1 ]
Steiner, H [1 ]
机构
[1] Schillerst Ludwig Maximilians Univ Munich 44, Adolf Butenandt Inst, Dept Biochem, Lab Alzheimers Dis Res, D-80336 Munich, Germany
关键词
D O I
10.1038/nn0901-859
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
A newly identified Alzheimer's mutation leads to the suggestion that protofibril intermediates In amyloid plaque formation may be a crucial factor in pathogenicity.
引用
收藏
页码:859 / 860
页数:2
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