Stevens-Johnson syndrome resulting from whole-brain radiation and phenytoin

被引：30

作者：

Cockey, GH

Amann, ST

Reents, SB

Lynch, JW

机构：

[1] UNIV FLORIDA,COLL MED,GAINESVILLE,FL

[2] SUN CTR W,GAINESVILLE,FL

[3] SHANDS HOSP,GAINESVILLE,FL

来源：

AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS | 1996年 / 19卷 / 01期

关键词：

whole-brain radiation; phenytoin; Stevens-Johnson syndrome;

D O I：

10.1097/00000421-199602000-00007

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Phenytoin, one of the most widely prescribed anticonvulsants, and steroids are routinely utilized for seizure prophylaxis in patients with various intracranial tumors. We report a case of severe Stevens-Johnson syndrome (SJS), documented by biopsy, which occurred in a patient, with metastatic squamous cell carcinoma receiving phenytoin, whole-brain radiation therapy (WBRT), and a tapering steroid dose. The pathogenesis and implications are then briefly discussed.

引用

页码：32 / 34

页数：3

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