Meningococcal disease and prevention at the Hajj

被引：33

作者：

Borrow, Ray ^{[1
]}

机构：

[1] Manchester Royal Infirm, Vaccine Evaluat Unit, Hlth Protect Agcy NW, Manchester M13 9WZ, Lancs, England

来源：

TRAVEL MEDICINE AND INFECTIOUS DISEASE | 2009年 / 7卷 / 04期

关键词：

Meningococcal; Hajj; Vaccine; Travel; Pilgrimage; DIPHTHERIA CONJUGATE VACCINE; MENINGITIDIS SEROGROUP W135; NEISSERIA-MENINGITIDIS; POLYSACCHARIDE VACCINATION; SAUDI CHILDREN; RISK-FACTORS; IMMUNOGENICITY; EPIDEMIC; CARRIAGE; OUTBREAK;

D O I：

10.1016/j.tmaid.2009.05.003

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The Islamic Hajj pilgrimage to Mecca, Kingdom of Saudi Arabia (KSA) has historically been associated with outbreaks of Neisseria meningitidis serogroup A. The main means of prevention against meningococcal disease was the bivalent serogroup A/C polysaccharide vaccine. During the Hajj pilgrimages of 2000 and 2001, there was an epidemiological shift from serogroup A disease to serogroup W135 disease together with an increase in incidence in younger age groups. This prompted the Ministry of Health to introduce quadrivalent ACYW135 polysaccharide vaccines. These interventions have quelled meningococcal disease since 2002. Trials on meningococcal quadrivalent conjugate vaccines are now underway in the KSA. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：219 / 225

页数：7

共 63 条

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