Reduction of cyclosporine-induced gingival overgrowth following a change to tacrolimus. A case history involving a liver transplant patient

被引：29

作者：

Bader, G

Lejeune, S

Messner, M

机构：

[1] CHRU Rennes, Serv Pathol & Chirurg Buccale, UFR Odontol, F-35000 Rennes, France

[2] Novartis Pharma SA Labs, Sandimmun, Basel, Switzerland

[3] Synthe Labs, Dihydan, Meudon, France

[4] Smithkline Beecham Labs, Augmentin, Nanterre, France

[5] Roussel Labs Ltd, Clarofam, Paris, France

[6] Leo Labs SA, Fucidine, St Quentin, France

来源：

JOURNAL OF PERIODONTOLOGY | 1998年 / 69卷 / 06期

关键词：

cyclosporin A adverse effects; tacrolimus therapeutic use; gingival hyperplasia etiology; immunosuppression;

D O I：

10.1902/jop.1998.69.6.729

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

DURING IMMUNOSUPPRESSION With cyclosporine, gingival overgrowth, a minor secondary effect, may appear in the first weeks of treatment. In certain cases it may affect the function and/or esthetic appearance in a manner intolerable to the patient. A new immunnosuppressive molecule, tacrolimus, presently used as a treatment of second choice to control acute corticoresistant rejection, may bring oral comfort to these patients, since it reduces gingival overgrowth to negligible levels.

引用

页码：729 / 732

页数：4

共 11 条

[1] CYCLOSPORINE-INDUCED GINGIVAL OVERGROWTH - AN ULTRASTRUCTURAL STEREOLOGIC STUDY [J].