Closed loop controlled administration of propofol using bispectral analysis

被引：105

作者：

Mortier, E ^{[1
]}

Struys, M ^{[1
]}

De Smet, T ^{[1
]}

Versichelen, L ^{[1
]}

Rolly, G ^{[1
]}

机构：

[1] State Univ Ghent Hosp, Dept Anaesthet, B-9000 Ghent, Belgium

来源：

ANAESTHESIA | 1998年 / 53卷 / 08期

关键词：

anaesthetics; intravenous; propofol; measurement techniques; bispectral analysis;

D O I：

10.1046/j.1365-2044.1998.00467.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Ten patients, undergoing elective orthopaedic surgery under spinal anaesthesia, were sedated with propofol using a closed-loop feedback control system. The bispectral index (BIS), a new processed EEG parameter, was used as control variable. Propofol administration was controlled by a patient individualised adaptive model-based controller incorporating target-controlled infusion technology combined with a pharmacokinetic-dynamic model. This feedback control system for propofol administration proved to be adequate and safe. BIS was found to be well suited as control variable.

引用

页码：749 / 754

页数：6

共 32 条

[1] A comparison of spectral edge, delta power, and bispectral index as EEG measures of alfentanil, propofol, and midazolam drug effect
Billard, V
Gambus, PL
Chamoun, N
Stanski, DR
Shafer, SL
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1997, 61 (01) : 45 - 58
[2] CHERNIK DA, 1990, J CLIN PSYCHOPHARM, V10, P244
[3] DUTTON RC, 1987, CONSCIOUSNESS AWAREN, P72
[4] CEREBRAL EFFECTS OF HIGH-DOSE MIDAZOLAM AND SUBSEQUENT REVERSAL WITH RO 15-1788 IN DOGS
FLEISCHER, JE
MILDE, JH
MOYER, TP
MICHENFELDER, JD
[J]. ANESTHESIOLOGY, 1988, 68 (02) : 234 - 242
[5] Bispectral analysis measures sedation and memory effects of propofol, midazolam, isoflurane, and alfentanil in healthy volunteers
Glass, PS
Bloom, M
Kearse, L
Rosow, C
Sebel, P
Manberg, P
[J]. ANESTHESIOLOGY, 1997, 86 (04) : 836 - 847
[6] A MODEL FOR STUDYING DEPTH OF ANESTHESIA AND ACUTE TOLERANCE TO THIOPENTAL
HUDSON, RJ
STANSKI, DR
SAIDMAN, LJ
MEATHE, E
[J]. ANESTHESIOLOGY, 1983, 59 (04) : 301 - 308
[7] DOES OPIOID ANESTHESIA EXIST
HUG, CC
[J]. ANESTHESIOLOGY, 1990, 73 (01) : 1 - 4
[8] JACOBS JR, 1993, ANESTH ANALG, V76, P1
[9] Infusion rate control algorithms for pharmacokinetic model-driven drug infusion devices
Jacobs, JR
[J]. INTERNATIONAL ANESTHESIOLOGY CLINICS, 1995, 33 (03) : 65 - 82
[10] BISPECTRAL ANALYSIS OF THE ELECTROENCEPHALOGRAM CORRELATES WITH PATIENT MOVEMENT TO SKIN INCISION DURING PROPOFOL NITROUS-OXIDE ANESTHESIA
KEARSE, LA
MANBERG, P
CHAMOUN, N
DEBROS, F
ZASLAVSKY, A
[J]. ANESTHESIOLOGY, 1994, 81 (06) : 1365 - 1370

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