Chk-ing in and Chk-ing out: Kinase Compartmentalization Comes to Checkpoint Control

被引:5
作者
Canton, David A. [1 ,2 ]
Scott, John D. [1 ,2 ]
机构
[1] Univ Washington, Howard Hughes Med Inst, Seattle, WA 98195 USA
[2] Univ Washington, Dept Pharmacol, Seattle, WA 98195 USA
关键词
D O I
10.1016/j.molcel.2010.09.020
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:1 / 2
页数:2
相关论文
共 10 条
[1]   Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase [J].
Bulavin, DV ;
Higashimoto, Y ;
Popoff, IJ ;
Gaarde, WA ;
Basrur, V ;
Potapova, O ;
Appella, E ;
Fornace, AJ .
NATURE, 2001, 411 (6833) :102-107
[2]  
GAESTEL M, 2006, MOL CELL, V28, P739
[3]   The DNA damage response: Ten years after [J].
Harper, J. Wade ;
Elledge, Stephen J. .
MOLECULAR CELL, 2007, 28 (05) :739-745
[4]   Cytokine-Induced Signaling Networks Prioritize Dynamic Range over Signal Strength [J].
Janes, Kevin A. ;
Reinhardt, H. Christian ;
Yaffe, Michael B. .
CELL, 2008, 135 (02) :343-354
[5]   MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation [J].
Manke, IA ;
Nguyen, A ;
Lim, D ;
Stewart, MQ ;
Elia, AEH ;
Yaffe, MB .
MOLECULAR CELL, 2005, 17 (01) :37-48
[6]   MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels [J].
Neininger, A ;
Kontoyiannis, D ;
Kotlyarov, A ;
Winzen, R ;
Eckert, R ;
Volk, HD ;
Holtmann, H ;
Kollias, G ;
Gaestel, M .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (05) :3065-3068
[7]   Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach [J].
O'Neill, T ;
Giarratani, L ;
Chen, P ;
Iyer, L ;
Lee, CH ;
Bobiak, M ;
Kanai, F ;
Zhou, BB ;
Chung, JH ;
Rathbun, GA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (18) :16102-16115
[8]   p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage [J].
Reinhardt, H. Christian ;
Aslanian, Aaron S. ;
Lees, Jacqueline A. ;
Yaffe, Michael B. .
CANCER CELL, 2007, 11 (02) :175-189
[9]   DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization [J].
Reinhardt, H. Christian ;
Hasskamp, Pia ;
Schmedding, Ingolf ;
Morandell, Sandra ;
van Vugt, Marcel A. T. M. ;
Wang, XiaoZhe ;
Linding, Rune ;
Ong, Shao-En ;
Weaver, David ;
Carr, Steven A. ;
Yaffe, Michael B. .
MOLECULAR CELL, 2010, 40 (01) :34-49
[10]   Cell Signaling in Space and Time: Where Proteins Come Together and When They're Apart [J].
Scott, John D. ;
Pawson, Tony .
SCIENCE, 2009, 326 (5957) :1220-1224