Integrons and gene cassettes in the Enterobacteriaceae

被引：393

作者：

White, PA ^{[1
]}

McIver, CJ

Rawlinson, WD

机构：

[1] Prince Wales Hosp, Dept Microbiol, Div Virol, SEALS, Randwick, NSW 2031, Australia

[2] Univ New S Wales, Fac Med, Sch Pathol, Sydney, NSW 2052, Australia

[3] Univ New S Wales, Fac Sci, Sch Microbiol & Immunol, Sydney, NSW 2052, Australia

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 09期

关键词：

D O I：

10.1128/AAC.45.9.2658-2661.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Integrons were detected in 59 of 120 (49%) urinary isolates of Enterobacteriaceae by PCR using degenerate primers targeted to conserved regions of class 1, 2, and 3 integrase genes. PCR sequencing analysis of the cassette arrays revealed a predominance of cassettes that confer resistance to the aminoglycosides and trimethoprim.

引用

页码：2658 / 2661

页数：4

共 24 条

[1] A NOVEL INTEGRON-LIKE ELEMENT CARRYING THE METALLO-BETA-LACTAMASE GENE BLA(IMP) [J].

ARAKAWA, Y ;

MURAKAMI, M ;

SUZUKI, K ;

ITO, H ;

WACHAROTAYANKUN, R ;

OHSUKA, S ;

KATO, N ;

OHTA, M .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (07) :1612-1615

[2]

Barrow GI., 1993, COWAN STEELS MANUAL, V3th

[3] Incidence and characterization of integrons, genetic elements mediating multiple-drug resistance, in avian Escherichia coli [J].

Bass, L ;

Liebert, CA ;

Lee, MD ;

Summers, AO ;

White, DG ;

Thayer, SG ;

Maurer, JJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (12) :2925-2929

[4] ADDITIONS AND MODIFICATIONS TO THE RANGE OF ANTIBIOTICS TESTED BY THE CDS METHOD OF ANTIBIOTIC-SENSITIVITY TESTING [J].

BELL, SM .

PATHOLOGY, 1988, 20 (03) :303-304

[5]

BELL SM, 1975, PATHOLOGY, V7, P1

[6] The integrons In0, In2, and In5 are defective transposon derivatives [J].

Brown, HJ ;

Stokes, HW ;

Hall, RM .

JOURNAL OF BACTERIOLOGY, 1996, 178 (15) :4429-4437

[7] NEW MOBILE GENE CASSETTES CONTAINING AN AMINOGLYCOSIDE RESISTANCE GENE, AACA7, AND A CHLORAMPHENICOL RESISTANCE GENE, CATB3, IN AN INTEGRON IN PBWH301 [J].

BUNNY, KL ;

HALL, RM ;

STOKES, HW .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (03) :686-693

[8] EXPRESSION OF ANTIBIOTIC-RESISTANCE GENES IN THE INTEGRATED CASSETTES OF INTEGRONS [J].

COLLIS, CM ;

HALL, RM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (01) :155-162

[9] GENE CASSETTES FROM THE INSERT REGION OF INTEGRONS ARE EXCISED AS COVALENTLY CLOSED CIRCLES [J].

COLLIS, CM ;

HALL, RM .

MOLECULAR MICROBIOLOGY, 1992, 6 (19) :2875-2885

[10]

Craig NL, 1996, CURR TOP MICROBIOL, V204, P27

← 1 2 3 →