Bioactive materials in endodontics

被引：44

作者：

Enkel, Benedicte ^{[2
]}

Dupas, Cecile ^{[1
]}

Armengol, Valerie ^{[1
]}

Adou, Jonas Akpe

Bosco, Julia ^{[1
]}

Daculsi, Guy ^{[1
]}

Jean, Alain ^{[2
]}

Laboux, Olivier ^{[2
]}

LeGeros, Racquel Z. ^{[3
]}

Weiss, Pierre ^{[1
]}

机构：

[1] Nantes Univ Hosp, Fac Chirurg Dent, INSERM, LIOAD,UMR S 791, F-44042 Nantes 01, France

[2] Nantes Univ Hosp, Fac Chirurg Dent, ERT Equipe Rech Clin Odontol & Chirurg Osseuse 10, F-44042 Nantes 01, France

[3] NYU, Coll Dent, Dept Biomat & Biomimet, New York, NY 10010 USA

来源：

EXPERT REVIEW OF MEDICAL DEVICES | 2008年 / 5卷 / 04期

关键词：

bioactivity; biomineralization; calcium phosphate; endodontics; injectable bone substitute; tissue engineering;

D O I：

10.1586/17434440.5.4.475

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

Endodontic treatment in dentistry is a delicate procedure and many treatment attempts fail. Despite constant development of new root canal filling techniques, the clinician is confronted with both a complex root canal system and the use of filling materials that are harmful for periapical tissues. This paper evaluates reported studies on biomaterials used in endodontics, including calcium hydroxide, mineral trioxide aggregate, calcium phosphate ceramics and calcium phosphate cements. Special emphasis is made on promising new biomaterials, such as injectable bone substitute and injectable calcium phosphate cements. These materials, which combine biocompatibility, bioactivity and rheological properties, could be good alternatives in endodontics as root canal fillers. They could also be used as drug-delivery vehicles (e.g., for antibiotics and growth factors) or as scaffolds in pulp tissue engineering.

引用

页码：475 / 494

页数：20

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