Sex-dependent gene expression and evolution of the Drosophila transcriptome

被引：502

作者：

Ranz, JM ^{[1
]}

Castillo-Davis, CI ^{[1
]}

Meiklejohn, CD ^{[1
]}

Hartl, DL ^{[1
]}

机构：

[1] Harvard Univ, Dept Organism & Evolutionary Biol, Cambridge, MA 02138 USA

来源：

SCIENCE | 2003年 / 300卷 / 5626期

关键词：

D O I：

10.1126/science.1085881

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Comparison of the gene-expression profiles between adults of Drosophila melanogaster and Drosophila simulans has uncovered the evolution of genes that exhibit sex-dependent regulation. Approximately half the genes showed differences in expression between the species, and among these, similar to83% involved a gain, loss, increase, decrease, or reversal of sex-biased expression. Most of the interspecific differences in messenger RNA abundance affect male-biased genes. Genes that differ in expression between the species showed functional clustering only if they were sex-biased. Our results suggest that sex-dependent selection may drive changes in expression of many of the most rapidly evolving genes in the Drosophila transcriptome.

引用

页码：1742 / 1745

页数：4

共 31 条

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