Structural biology - A 3D view of sodium channels

被引：33

作者：

Catterall, WA ^{[1
]}

机构：

[1] Univ Washington, Sch Med, Dept Pharmacol, Seattle, WA 98195 USA

来源：

NATURE | 2001年 / 409卷 / 6823期

关键词：

D O I：

10.1038/35059188

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The voltage-gated sodium channel is essential for nerve cells to function. But how does it work? A low-resolution, three-dimensional structure provides some provocative insights.

引用

页码：988 / 991

页数：4

共 12 条

[1] IDENTIFICATION OF A LARGE MOLECULAR-WEIGHT PEPTIDE ASSOCIATED WITH A TETRODOTOXIN BINDING-PROTEIN FROM THE ELECTROPLAX OF ELECTROPHORUS-ELECTRICUS [J].

AGNEW, WS ;

MOORE, AC ;

LEVINSON, SR ;

RAFTERY, MA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 92 (03) :860-866

[2] COVALENT LABELING OF PROTEIN-COMPONENTS OF THE SODIUM-CHANNEL WITH A PHOTOACTIVABLE DERIVATIVE OF SCORPION TOXIN [J].

BENESKI, DA ;

CATTERALL, WA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (01) :639-643

[3] From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels [J].

Catterall, WA .

NEURON, 2000, 26 (01) :13-25

[4] Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy [J].

Cha, A ;

Snyder, GE ;

Selvin, PR ;

Bezanilla, F .

NATURE, 1999, 402 (6763) :809-813

[5] The structure of the potassium channel:: Molecular basis of K+ conduction and selectivity [J].

Doyle, DA ;

Cabral, JM ;

Pfuetzner, RA ;

Kuo, AL ;

Gulbis, JM ;

Cohen, SL ;

Chait, BT ;

MacKinnon, R .

SCIENCE, 1998, 280 (5360) :69-77

[6] Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel [J].

Glauner, KS ;

Mannuzzu, LM ;

Gandhi, CS ;

Isacoff, EY .

NATURE, 1999, 402 (6763) :813-817

[7] Nomenclature of voltage-gated sodium channels [J].

Goldin, AL ;

Barchi, RL ;

Caldwell, JH ;

Hofmann, F ;

Howe, JR ;

Hunter, JC ;

Kallen, RG ;

Mandel, G ;

Meisler, MH ;

Netter, YB ;

Noda, M ;

Tamkun, MM ;

Waxman, SG ;

Wood, JN ;

Catterall, WA .

NEURON, 2000, 28 (02) :365-368

[8] Voltage-gated ion channels and hereditary disease [J].

Lehmann-Horn, F ;

Jurkat-Rott, K .

PHYSIOLOGICAL REVIEWS, 1999, 79 (04) :1317-1372

[9] PRIMARY STRUCTURE OF ELECTROPHORUS-ELECTRICUS SODIUM-CHANNEL DEDUCED FROM CDNA SEQUENCE [J].

NODA, M ;

SHIMIZU, S ;

TANABE, T ;

TAKAI, T ;

KAYANO, T ;

IKEDA, T ;

TAKAHASHI, H ;

NAKAYAMA, H ;

KANAOKA, Y ;

MINAMINO, N ;

KANGAWA, K ;

MATSUO, H ;

RAFTERY, MA ;

HIROSE, T ;

INAYAMA, S ;

HAYASHIDA, H ;

MIYATA, T ;

NUMA, S .

NATURE, 1984, 312 (5990) :121-127

[10] Solution structure of the sodium channel inactivation gate [J].

Rohl, CA ;

Boeckman, FA ;

Baker, C ;

Scheuer, T ;

Catterall, WA ;

Klevit, RE .

BIOCHEMISTRY, 1999, 38 (03) :855-861

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