Preparation of substituted anilines from nitro compounds by using supported gold catalysts

被引：41

作者：

Corma, Avelino ^{[1
]}

Serna, Pedro ^{[1
]}

机构：

[1] Univ Politecn Valencia, CSIC, Inst Tecnol Quim, Valencia 46022, Spain

来源：

NATURE PROTOCOLS | 2006年 / 1卷 / 06期

关键词：

D O I：

10.1038/nprot.2006.441

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A protocol for the chemoselective hydrogenation of nitro compounds to the corresponding anilines by means of supported gold catalysts is described. Nitro groups on different compounds - containing double bonds, carbonyl, nitrile or amide groups - have been successfully hydrogenated on supported gold nanoparticles (Au/ TiO(2) and Au/Fe(2)O(3)), using a batch reactor under H(2) pressure. Unlike other noble metals, gold shows high chemoselectivity towards reduction of the nitro group, at near-complete conversion of the substrate. The total time to carry out this protocol strongly depends on the reaction step, which is a function of the activity of the catalyst and the nature of the substrate.

引用

页码：2590 / 2595

页数：6

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