Adjunctive therapy in epilepsy with new antiepileptic drugs: is it of any value?

被引：11

作者：

Selai, CE ^{[1
]}

Trimble, MR ^{[1
]}

机构：

[1] Inst Neurol, Raymond Way Neuropsychiat Unit, London WC1N 3BG, England

来源：

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 1998年 / 7卷 / 05期

关键词：

epilepsy; quality-of-life; vigabatrin; clobazam; lamotrigine; gabapentin;

D O I：

10.1016/S1059-1311(05)80014-7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A total of 97 patients were recruited into a prospective, follow-up study after they were prescribed an adjunctive antiepileptic drug. The patients were followed up over a 6-month period. The interview included questions on Quality of Life, side-effects, adverse events and seizure frequency and severity. We operationally defined patients 'satisfaction' as (i) still on new drug; (ii) experiencing no side-effects (iii) experiencing no adverse events and (iv) had a greater than 50% reduction in seizures. A total of 13 patients (17%) reported being 'satisfied' according to our operational definition.

引用

页码：417 / 418

页数：2