Comparison of intracytoplasmic sperm injection for inbred and hybrid mice

被引：45

作者：

Kawase, Y

Iwata, T

Toyoda, Y

Wakayama, T

Yanagimachi, R

Suzuki, H ^{[1
]}

机构：

[1] Obihiro Univ Agr & Vet Med, Natl Res Ctr Protozoan Dis, Obihiro, Hokkaido 0808555, Japan

[2] Chugai Pharmaceut Co Ltd, Pharmaceut Technol Lab, Shizuoka, Japan

[3] Univ Hawaii, Sch Med, Dept Anat & Reprod Biol, Inst Biogenesis Res, Honolulu, HI 96822 USA

来源：

MOLECULAR REPRODUCTION AND DEVELOPMENT | 2001年 / 60卷 / 01期

关键词：

fertilization; development; oocyte; sperm; intracytoplasmic;

D O I：

10.1002/mrd.1063

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

We compared the results of intracytoplasmic sperm injection (ICSI) that leads to full term development of hybrid (B6C3F1 and B6D2F1) and inbred (C57BL/6) mouse embryos. Although fertilization and pre-im plantation development of C57BL/6 eggs were similar to those of F1 hybrid eggs, post-implantation development of the embryos from C57BL/6 females was significantly poorer than those of the eggs from hybrid females. Reciprocal crosses of C57BL/6 and B6C3F1 gametes revealed that the low rate of post-implantation development of C57BL/6 embryos was due to oocyte factor(s), rather than the sperm factor.

引用

页码：74 / 78

页数：5

共 33 条

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