Associations of HLA-shared epitope, anti-citrullinated peptide antibodies and lifestyle-related factors in Hungarian patients with rheumatoid arthritis: Data from the first Central-Eastern European cohort

被引:8
作者
Besenyei, Timea [1 ,2 ]
Gyetvai, Agnes [2 ,3 ]
Szabo, Zoltan [1 ,2 ]
Fekete, Andrea [2 ,3 ]
Kapitany, Aniko [2 ,3 ]
Szodoray, Peter [4 ]
Laki, Judit [5 ]
Soos, Lilla [1 ,2 ]
Sipka, Sandor [2 ,3 ]
Szegedi, Gyula [6 ]
Lakos, Gabriella [2 ,3 ,7 ]
Szekanecz, Zoltan [1 ,2 ]
机构
[1] Univ Debrecen, Dept Rheumatol, Inst Med, H-4012 Debrecen, Hungary
[2] Hlth Sci Ctr, H-4012 Debrecen, Hungary
[3] Univ Debrecen, Immunol Lab, Dept Med 3, Inst Med, H-4012 Debrecen, Hungary
[4] Univ Oslo, Rikshosp, Inst Immunol, N-0027 Oslo, Norway
[5] Natl Med Ctr, Dept Rheumatol, Budapest, Hungary
[6] Hungarian Acad Sci, Autoimmune Dis Res Grp, Debrecen, Hungary
[7] TheraTest Labs Inc, Lombard, IL USA
关键词
Rheumatoid arthritis; Shared epitope; Anti-citrullinated protein antibodies; Anti-CCP; Rheumatoid factor; Smoking; Alcohol; PROTEIN ANTIBODIES; SUSCEPTIBILITY; AUTOANTIBODIES; CLASSIFICATION; HYPOTHESIS; ALLELES; SMOKING; RISK;
D O I
10.1016/j.jbspin.2011.05.018
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
引用
收藏
页码:652 / 653
页数:3
相关论文
共 10 条
[1]
New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility [J].
du Montcel, ST ;
Michou, L ;
Petit-Teixeira, E ;
Osorio, J ;
Lemaire, I ;
Lasbleiz, S ;
Pierlot, U ;
Quillet, P ;
Bardin, T ;
Prum, B ;
Cornelis, FO ;
Clerget-Darpoux, F .
ARTHRITIS AND RHEUMATISM, 2005, 52 (04) :1063-1068
[2]
THE SHARED EPITOPE HYPOTHESIS - AN APPROACH TO UNDERSTANDING THE MOLECULAR-GENETICS OF SUSCEPTIBILITY TO RHEUMATOID-ARTHRITIS [J].
GREGERSEN, PK ;
SILVER, J ;
WINCHESTER, RJ .
ARTHRITIS AND RHEUMATISM, 1987, 30 (11) :1205-1213
[3]
New classification of the shared epitope in rheumatoid arthritis: impact on the production of various anti-citrullinated protein antibodies [J].
Gyetvai, Agnes ;
Szekanecz, Zoltan ;
Soos, Lilla ;
Szabo, Zoltan ;
Fekete, Andrea ;
Kapitany, Aniko ;
Teodorescu, Marius ;
Sipka, Sandor ;
Szegedi, Gyula ;
Lakos, Gabriella .
RHEUMATOLOGY, 2010, 49 (01) :25-33
[4]
Antibodies to citrullinated proteins in arthritis:: pathology and promise [J].
Klareskog, Lars ;
Widhe, Mona ;
Hermansson, Monika ;
Ronnelid, Johan .
CURRENT OPINION IN RHEUMATOLOGY, 2008, 20 (03) :300-305
[5]
Reevaluation of the Interaction Between HLA-DRB1 Shared Epitope Alleles, PTPN22, and Smoking in Determining Susceptibility to Autoantibody-Positive and Autoantibody-Negative Rheumatoid Arthritis in a Large UK Caucasian Population [J].
Morgan, Ann W. ;
Thomson, Wendy ;
Martin, Stephen G. ;
Carter, Angela M. ;
Erlich, Henry A. ;
Barton, Anne ;
Hocking, Lynne ;
Reid, David M. ;
Harrison, Pille ;
Wordsworth, Paul ;
Steer, Sophia ;
Worthington, Jane ;
Emery, Paul ;
Wilson, Anthony G. ;
Barrett, Jennifer H. .
ARTHRITIS AND RHEUMATISM, 2009, 60 (09) :2565-2576
[6]
A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis [J].
Padyukov, L ;
Silva, C ;
Stolt, P ;
Alfredsson, L ;
Klareskog, L .
ARTHRITIS AND RHEUMATISM, 2004, 50 (10) :3085-3092
[7]
Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptides [J].
Pedersen, Merete ;
Jacobsen, Soren ;
Klarlund, Mette ;
Pedersen, Bo V. ;
Wiik, Allan ;
Wohlfahrt, Jan ;
Frisch, Morten .
ARTHRITIS RESEARCH & THERAPY, 2006, 8 (04)
[8]
Anti-citrullinated protein antibodies in rheumatoid arthritis:: As good as it gets? [J].
Szekanecz, Zoltan ;
Soos, Lilla ;
Szabo, Zoltan ;
Fekete, Andrea ;
Kapitany, Aniko ;
Vegvari, Aniko ;
Sipka, Sandor ;
Szucs, Gabriella ;
Szanto, Sandor ;
Lakos, Gabriella .
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2008, 34 (01) :26-31
[9]
Anti-citrullinated protein/peptide autoantibodies in association with genetic and environmental factors as indicators of disease outcome in rheumatoid arthritis [J].
Szodoray, Peter ;
Szabo, Zoltan ;
Kapitany, Aniko ;
Gyetvai, Agnes ;
Lakos, Gabriella ;
Szanto, Sandor ;
Szucs, Gabriella ;
Szekanecz, Zoltan .
AUTOIMMUNITY REVIEWS, 2010, 9 (03) :140-143
[10]
Understanding the genetic contribution to rheumatoid arthritis [J].
van der Helm-van Mil, AHM ;
Wesoly, JZ ;
Huizinga, TWJ .
CURRENT OPINION IN RHEUMATOLOGY, 2005, 17 (03) :299-304