Do morphology and stage explain the inferior lung cancer survival in Denmark?

被引:35
作者
Storm, HH [1 ]
Dickman, PW
Engeland, A
Haldorsen, T
Hakulinen, T
机构
[1] Danish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark
[2] Univ Newcastle, Dept Stat, Newcastle, NSW 2308, Australia
[3] Natl Publ Hlth Inst, Dept Populat Hlth Sci, Oslo, Norway
[4] Canc Registry Norway, Oslo, Norway
[5] Finnish Canc Registry, FIN-00170 Helsinki, Finland
[6] Univ Helsinki, Dept Publ Hlth, Helsinki, Finland
关键词
cancer registries; epidemiology; lung; morphology; stage; survival;
D O I
10.1183/09031936.99.13243099
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Danish lung cancer patients diagnosed during 1983-1987 experienced 5-yr relative survival rates 2-7% inferior to patients in the other Nordic countries, despite the similarity of cancer registration and healthcare systems in the Nordic countries,Is the inferior relative survival in Denmark due to differences in morphology or stage of lung cancers? The present study compared in detail the survival of 92;719 patients diagnosed with lung cancer during 1978-1992 in Denmark, Finland, and Norway, In particular, differences in morphology and extent of disease were studied, A poor survival rate for small cell anaplastic lung carcinoma compared with all other morphologies was confirmed. However, this could not explain the relative survival differences observed between countries. Extent of disease was the most important predictor of survival. Part of the observed survival differences could be explained by a less favourable stage distribution in Denmark, combined,vith a slightly lo,ver relative survival rate for those with metastatic disease. Differences in treatment are unlikely to explain the findings, although delays in diagnosing and treating patients in Denmark compared with neighbouring countries could partially explain the lower patient survival in Denmark, In conclusion, the main factor in the lower survival rate in Denmark is unfavourable stage distribution.
引用
收藏
页码:430 / 435
页数:6
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