Influence of haemoglobin Concentration and peripheral muscle pO2 on tumour oxygenation in advanced head and neck tumours

被引：22

作者：

Clavo, B

Pérez, JL

López, L

Suárez, G

Lloret, M

Morera, J

Macías, D

Martínez, JC

Santana, M

Hernández, MA

Robaina, F

Günderoth, M

机构：

[1] Dr Negrin Hosp, Dept Radiat Oncol & Res Unit, Las Palmas Gran Canaria 35020, Canary Islands, Spain

[2] Dr Negrin Hosp, Dept Med Phys, Las Palmas Gran Canaria, Canary Islands, Spain

[3] Dr Negrin Hosp, Dept Funct & Stereotact Neurosurg, Las Palmas Gran Canaria, Canary Islands, Spain

[4] NaSa de la Candelaria Hosp, Dept Radiat Oncol, Tenerife, Canary Islands, Spain

[5] Helzel Med Syst, Kaltenkirchen, Germany

来源：

RADIOTHERAPY AND ONCOLOGY | 2003年 / 66卷 / 01期

关键词：

hemoglobin; hypoxia; muscle oxygenation; oxygen measurement; polarographic probe; tumor oxygenation;

D O I：

10.1016/S0167-8140(02)00391-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Haemoglobin concentrations and tumour-pO(2) were evaluated pre-therapy in 30 patients with head and neck cancers. Anterior tibialis muscle-pO(2) was additionally measured in 16 of these patients. Tumour-pO(2) was lower in the most anaemic patients (P = 0.032) and correlated with muscle-PO2 (r = 0.809, P < 0.001). These results suggest that haemoglobin concentration influences tumour-oxygenation. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：71 / 74

页数：4

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