Characterization of long-term cultures of hepatitis C virus

被引：112

作者：

Nakajima, N ^{[1
]}

Hijikata, M ^{[1
]}

Yoshikura, H ^{[1
]}

Shimizu, YK ^{[1
]}

机构：

[1] UNIV TOKYO,FAC MED,DEPT HEPATITIS VIRUSES SMITHKLINE BEECHMAN BIOL,BUNKYO KU,TOKYO 113,JAPAN

来源：

JOURNAL OF VIROLOGY | 1996年 / 70卷 / 05期

关键词：

D O I：

10.1128/JVI.70.5.3325-3329.1996

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The human T- and B-cell lines HPBMa10-2 and Daudi produced infectious hepatitis C virus (HCV) for more than 1 year after infection. The infectivity titer of the cell culture-grown HCV and its genome titer were comparable. The virion density in sucrose was around 1.12 g/ml. Among the 13 variants detected in the inoculum, 7 were adsorbed by the cells and one particular HCV sequence which was present in minor quantities in the inoculum persisted.

引用

页码：3325 / 3329

页数：5

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