Cystic echinococcosis in semi-nomadic pastoral communities in north-west China

被引:72
作者
Wang, YH
Rogan, MT
Vuitton, DA
Wen, H
Bartholomot, B
Macpherson, CNL
Zou, PF
Ding, ZX
Zhou, HX
Zhang, XF
Luo, J
Xiong, HB
Fu, Y
McVie, A
Giraudoux, P
Yang, WG
Craig, PS [1 ]
机构
[1] Univ Salford, Sch Environm & Life Sci, Div Biol Sci, Cestode Zoonoses Res Grp, Salford M5 4WT, Lancs, England
[2] Xinjiang Med Univ, Teaching Hosp 1, Dept Gen Surg, Urumai 830000, Peoples R China
[3] Univ Franche Comte, WHO Collaborating Ctr Prevent & Treatment Echinoc, SERF Res Unit EA 2276, F-25030 Besancon, France
关键词
cystic echinococcosis; Echinococcus granulosus; epidemiology; ultrasound; ethnic groups; risk factors; dogs; coproantigen; surgery; chemotherapy; PAIR; China;
D O I
10.1016/S0035-9203(01)90142-7
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In order to determine the prevalence of human cystic echinococcosis (CE) in semi-nomadic traditional pastoralist groups in north-west China, 2 large community studies were undertaken in Altai and Tacheng Prefectures in 1990/91 and 1995/96, respectively. The Kekergash community (Altai) comprised mainly ethnic Kazakhs, whereas the Narenhebuke community (Tacheng) comprised mainly Mongolians. Populations were screened for CE by abdominal ultrasound scan (US) and serological tests. The total prevalence of confirmed human CE was higher in Narenhebuke (27%, 49/1844) than in Kekergash (0.9%, 17/1861; P < 0.01). Within each community there was no significant difference of CE prevalence between the Kazakh and Mongolian groups, although Han Chinese exhibited twice the rate of CE (4.9%) in Narenhebuke compared to the dominant Mongolian population For each community, human CE prevalence increased with age and there was a greater risk associated with the practice of home slaughter of livestock. Dogs were screened for Echinococcus granulosus infection and re-infection levels using a highly specific coproantigen test. The proportion of dogs with positive coproantigen tests was significantly higher in Narenhebuke (36.0%, 50/139) compared to Kekergash (17.8%, 16/90). In Narenhebuke the re-infection levels of dogs, as determined by coproantigen positivity, were higher in the winter quarters (49.4%, 39/79) compared to the summer quarters (18.3%, 11/60; P < 0.01). Furthermore, coproantigen re-test positivity was 25% at 3 months and 29.2% at 7 months. Highest dog coproantigen positivity was obtained over the winter period.
引用
收藏
页码:153 / 158
页数:6
相关论文
共 31 条
[1]   COPROANTIGEN DETECTION FOR IMMUNODIAGNOSIS OF ECHINOCOCCOSIS AND TAENIASIS IN DOGS AND HUMANS [J].
ALLAN, JC ;
CRAIG, PS ;
NOVAL, JG ;
MENCOS, F ;
LIU, D ;
WANG, Y ;
WEN, H ;
ZHOU, P ;
STRINGER, R ;
ROGAN, M ;
ZEYHLE, E .
PARASITOLOGY, 1992, 104 :347-355
[2]   Public health importance of cystic echinococcosis in Latin America [J].
Arambulo, P .
ACTA TROPICA, 1997, 67 (1-2) :113-124
[3]   ECHINOCOCCUS-GRANULOSUS INFECTIONS IN THE DOGS OF KATHMANDU, NEPAL [J].
BARONET, D ;
WALTNERTOEWS, D ;
CRAIG, PS ;
JOSHI, DD .
ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 1994, 88 (05) :485-492
[4]   Risk factors associated with human cystic echinococcosis in Florida, Uruguay: Results of a mass screening study using ultrasound and serology [J].
Carmona, C ;
Perdomo, R ;
Carbo, A ;
Alvarez, C ;
Monti, J ;
Grauert, R ;
Stern, D ;
Perera, G ;
Lloyd, S ;
Bazini, R ;
Gemmell, MA ;
Yarzabal, L .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1998, 58 (05) :599-605
[5]  
Chai J. J., 1993, Compendium on cystic echinococcosis: with special reference to the Xinjiang Uygur Autonomous Region, The People's Republic of China., P16
[6]  
Chai Jun-Jie, 1995, Biomedical and Environmental Sciences, V8, P122
[7]  
CHI P, 1990, TROP MED PARASITOL, V41, P157
[8]  
Craig P.S., 1997, COMPENDIUM CYSTIC EC, P85
[9]   A LARGE FOCUS OF ALVEOLAR ECHINOCOCCOSIS IN CENTRAL CHINA [J].
CRAIG, PS ;
LIU, DS ;
MACPHERSON, CNL ;
SHI, DZ ;
REYNOLDS, D ;
BARNISH, G ;
GOTTSTEIN, B ;
WANG, ZR .
LANCET, 1992, 340 (8823) :826-831
[10]   Detection, screening and community epidemiology of Taeniid cestode zoonoses: Cystic echinococcosis, alveolar echinococcosis and neurocysticercosis [J].
Craig, PS ;
Rogan, MT ;
Allan, JC .
ADVANCES IN PARASITOLOGY, VOL 38, 1996, 38 :169-250