Soluble receptors for cytokines and growth factors

被引：27

作者：

MullerNewen, G ^{[1
]}

Kohne, C ^{[1
]}

Heinrich, PC ^{[1
]}

机构：

[1] KLINIKUM RWTH AACHEN,INST BIOCHEM,D-52057 AACHEN,GERMANY

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY | 1996年 / 111卷 / 02期

关键词：

cytokines; growth factors; soluble receptors; shedding; splicing; antagonists; agonistic action;

D O I：

10.1159/000237353

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Soluble cytokine and growth factor receptors are currently believed to play an important role in the regulation of biological activities of their ligands. In this review the current ideas on the mechanisms and regulation of generation of soluble receptors and their possible physiological functions are presented. Furthermore, implications of soluble cytokine and growth factor receptors as disease markers and therapeutical agents are summarized and discussed.

引用

页码：99 / 106

页数：8

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