Impenetrable barriers or entry portals? The role of cell-cell adhesion during infection

被引：53

作者：

Bonazzi, Matteo ^{[4
,5
,6
]}

Cossart, Pascale ^{[1
,2
,3
]}

机构：

[1] Inst Pasteur, Unite Interact Bacteries Cellules, F-75015 Paris, France

[2] Inst Natl Sante & Rech Med, U604, F-75015 Paris, France

[3] INRA, USC2020, F-75015 Paris, France

[4] Ctr Natl Rech Sci, UMR 5236, CPBS, CNRS, F-34293 Montpellier, France

[5] Univ Montpellier I, F-34293 Montpellier, France

[6] Univ Montpellier 2, F-34293 Montpellier, France

来源：

JOURNAL OF CELL BIOLOGY | 2011年 / 195卷 / 03期

基金：

欧洲研究理事会;

关键词：

HELICOBACTER-PYLORI CAGA; ENTEROPATHOGENIC ESCHERICHIA-COLI; HEPATITIS-C VIRUS; TIGHT JUNCTION PROTEINS; CLOSTRIDIUM-DIFFICILE TOXINS; INTESTINAL EPITHELIAL-CELLS; BACTERIAL VIRULENCE FACTOR; INNATE IMMUNE-RESPONSES; NF-KAPPA-B; LISTERIA-MONOCYTOGENES;

D O I：

10.1083/jcb.201106011

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cell-cell adhesion plays a fundamental role in cell polarity and organogenesis. It also contributes to the formation and establishment of physical barriers against microbial infections. However, a large number of pathogens, from viruses to bacteria and parasites, have developed countless strategies to specifically target cell adhesion molecules in order to adhere to and invade epithelial cells, disrupt epithelial integrity, and access deeper tissues for dissemination. The study of all these processes has contributed to the characterization of molecular machineries at the junctions of eukaryotic cells that have been better understood by using pathogens as probes.

引用

页码：348 / 357

页数：10

共 99 条

[1] Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA [J].

Amieva, MR ;

Vogelmann, R ;

Covacci, A ;

Tompkins, LS ;

Nelson, WJ ;

Falkow, S .

SCIENCE, 2003, 300 (5624) :1430-1434

[2] An injected bacterial effector targets chromatin access for transcription factor NF-κB to alter transcription of host genes involved in immune responses [J].

Arbibe, Laurence ;

Kim, Dong Wook ;

Batsche, Eric ;

Pedron, Thierry ;

Mateescu, Bogdan ;

Muchardt, Christian ;

Parsot, Claude ;

Sansonetti, Philippe J. .

NATURE IMMUNOLOGY, 2007, 8 (01) :47-56

[3] Junction adhesion molecule is a receptor for reovirus [J].

Barton, ES ;

Forrest, JC ;

Connolly, JL ;

Chappell, JD ;

Liu, Y ;

Schnell, FJ ;

Nusrat, A ;

Parkos, CA ;

Dermody, TS .

CELL, 2001, 104 (03) :441-451

[4]

Bassères DS, 2002, BIOCHEM BIOPH RES CO, V294, P579

[5] A protein kinase A-dependent mechanism by which rotavirus affects the distribution and mRNA level of the functional tight junction-associated protein, occludin, in human differentiated intestinal caco-2 cells [J].

Beau, Isabelle ;

Cotte-Laffitte, Jacqueline ;

Amsellem, Raymonde ;

Servin, Alain L. .

JOURNAL OF VIROLOGY, 2007, 81 (16) :8579-8586

[6] Isolation of a common receptor for coxsackie B viruses and adenoviruses 2 and 5 [J].

Bergelson, JM ;

Cunningham, JA ;

Droguett, G ;

KurtJones, EA ;

Krithivas, A ;

Hong, JS ;

Horwitz, MS ;

Crowell, RL ;

Finberg, RW .

SCIENCE, 1997, 275 (5304) :1320-1323

[7] Successive post-translational modifications of E-cadherin are required for InlA-mediated internalization of Listeria monocytogenes [J].

Bonazzi, Matteo ;

Veiga, Esteban ;

Pizarro-Cerda, Javier ;

Cossart, Pascale .

CELLULAR MICROBIOLOGY, 2008, 10 (11) :2208-2222

[8] Clathrin phosphorylation is required for actin recruitment at sites of bacterial adhesion and internalization [J].

Bonazzi, Matteo ;

Vasudevan, Lavanya ;

Mallet, Adeline ;

Sachse, Martin ;

Sartori, Anna ;

Prevost, Marie-Christine ;

Roberts, Allison ;

Taner, Sabrina B. ;

Wilbur, Jeremy D. ;

Brodsky, Frances M. ;

Cossart, Pascale .

JOURNAL OF CELL BIOLOGY, 2011, 195 (03) :525-536

[9] Listeria monocytogenes internalin and E-cadherin: from structure to pathogenesis [J].

Bonazzi, Matteo ;

Lecuit, Marc ;

Cossart, Pascale .

CELLULAR MICROBIOLOGY, 2009, 11 (05) :693-702

[10] Salmonella enterica serovar Typhimurium effectors SopB, SopE, SopE2 and SipA disrupt tight junction structure and function [J].

Boyle, Erin C. ;

Brown, Nat F. ;

Finlay, B. Brett .

CELLULAR MICROBIOLOGY, 2006, 8 (12) :1946-1957

← 1 2 3 4 5 6 7 8 9 10 →