Magnetoencephalography: From SQUIDs to neuroscience Neuroimage 20th Anniversary Special Edition

被引:173
作者
Hari, Riitta [1 ]
Salmelin, Riitta [1 ]
机构
[1] Aalto Univ, OV Lounasmaa Lab, Brain Res Unit, FI-00076 Espoo, Finland
基金
芬兰科学院; 欧洲研究理事会;
关键词
MEG; Human; Cortex; Timing; History; HUMAN AUDITORY-CORTEX; EVOKED MAGNETIC-FIELDS; HUMAN SOMATOSENSORY CORTEX; PRIMARY MOTOR CORTEX; RESTING STATE NETWORKS; HUMAN-BRAIN; CORTICAL REPRESENTATION; SPEECH-PERCEPTION; DYSLEXIC ADULTS; VISUAL-CORTEX;
D O I
10.1016/j.neuroimage.2011.11.074
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Magnetoencephalography (MEG), with its direct view to the cortex through the magnetically transparent skull, has developed from its conception in physics laboratories to a powerful tool of basic and clinical neuroscience. MEG provides millisecond time resolution and allows real-time tracking of brain activation sequences during sensory processing, motor planning and action, cognition, language perception and production, social interaction, and various brain disorders. Current-day neuromagnetometers house hundreds of SQUIDs, superconducting quantum interference devices, to pick up signals generated by concerted action of cortical neurons. Complementary MEG measures of neuronal involvement include evoked responses, modulation of cortical rhythms, properties of the on-going neural activity, and interareal connectivity. Future MEG breakthroughs in understanding brain dynamics are expected through advanced signal analysis and combined use of MEG with hemodynamic imaging (fMRI). Methodological development progresses most efficiently when linked with insightful neuroscientific questions. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:386 / 396
页数:11
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