Mycobacterium tuberculosis:: Here today, and here tomorrow

被引：598

作者：

Russell, DG ^{[1
]}

机构：

[1] Cornell Univ, Vet Med Ctr 5173, Ithaca, NY 14853 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2001年 / 2卷 / 08期

关键词：

D O I：

10.1038/35085034

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Mycobacterium tuberculosis is a highly successful pathogen that parasitizes the macrophages of its host. Its success can be attributed directly to its ability to manipulate the phagosome that it resides in and to prevent the normal maturation of this organelle into an acidic, hydrolytic compartment. As the macrophage is key to clearing the infection, the interplay between the pathogen and its host cell reflects a constant battle for control.

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页码：569 / 577

页数：9

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