Gene regulation - A paradigm for precision

被引：47

作者：

Struhl, K ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA

来源：

SCIENCE | 2001年 / 293卷 / 5532期

关键词：

D O I：

10.1126/science.1064050

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 [理学]; 0710 [生物学]; 09 [农学];

摘要：

引用

收藏

页码：1054 / 1055

页数：2

相关论文

共 15 条

[1]

Ordered recruitment of chromatin modifying and general transcription factors to the IFN-β promoter [J].

Agalioti, T ;

Lomvardas, S ;

Parekh, B ;

Yie, JM ;

Maniatis, T ;

Thanos, D .

CELL, 2000, 103 (04) :667-678

[2]

Assembly of a functional beta interferon enhanceosome is dependent on ATF-2-c-jun heterodimer orientation [J].

Falvo, JV ;

Parekh, BS ;

Lin, CH ;

Fraenkel, E ;

Maniatis, T .

MOLECULAR AND CELLULAR BIOLOGY, 2000, 20 (13) :4814-4825

[3]

Structure and function of the interferon-β enhanceosome [J].

Maniatis, T ;

Falvo, JV ;

Kim, TH ;

Kim, TK ;

Lin, CH ;

Parekh, BS ;

Wathelet, MG .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1998, 63 :609-620

[4]

Maniatis T, 1992, TRANSCRIPTIONAL REGU, P1193

[5]

Recruitment of CBP/p300 by the IFNβ enhanceosome is required for synergistic activation of transcription [J].

Merika, M ;

Williams, AJ ;

Chen, GY ;

Collins, T ;

Thanos, D .

MOLECULAR CELL, 1998, 1 (02) :277-287

[6]

Enhanceosomes [J].

Merika, M ;

Thanos, D .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2001, 11 (02) :205-208

[7]

Acetylation of HMG I(Y) by CBP turns off IFNβ expression by disrupting the enhanceosome [J].

Munshi, N ;

Merika, M ;

Yie, JM ;

Senger, K ;

Chen, GY ;

Thanos, D .

MOLECULAR CELL, 1998, 2 (04) :457-467

[8]

Coordination of a transcriptional switch by HMGI(Y) acetylation [J].

Munshi, N ;

Agalioti, T ;

Lomvardas, S ;

Merika, M ;

Chen, GY ;

Thanos, D .

SCIENCE, 2001, 293 (5532) :1133-1136

[9]

Transcriptional activation by recruitment [J].

Ptashne, M ;

Gann, A .

NATURE, 1997, 386 (6625) :569-577

[10]

MECHANISMS FOR DIVERSITY IN GENE-EXPRESSION PATTERNS [J].

STRUHL, K .

NEURON, 1991, 7 (02) :177-181