What causes prostate cancer? A brief summary of the epidemiology

被引:94
作者
Chan, JM
Stampfer, MJ
Giovannucci, EL
机构
[1] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[2] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA
[3] Harvard Univ, Sch Med, Brigham & Womens Hosp, Channing Lab,Dept Med, Boston, MA 02115 USA
关键词
prostate cancer; risk factors; epidemiology causes;
D O I
10.1006/scbi.1998.0075
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In recent decades, prostate cancer has emerged as one of the most common diseases among older men, particularly in Western society. Several years ago, only age, race, and family history were known risk factors for this disease. However, today, much progress has been made towards discovering nutritional and hormonal risk factors for prostate cancer. Biomarkers, including testosterone and insulin-like growth factor, and nutritional factors, especially meat, fat, and daily intake, have been linked to greater risk of disease. Higher consumption of selenium and vitamin E, fructose/fruits, and tomatoes all have been associated with reduced occurrence of prostate cancer, but as yet their efficacy for prevention remains unproven. The challenge of understanding the enigmas of this disease will continue into future decades, as we convert current Knowledge into preventive and therapeutic recommendations.
引用
收藏
页码:263 / 273
页数:11
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