Genome-wide association studies in plants: the missing heritability is in the field

被引：368

作者：

Brachi, Benjamin ^{[1
]}

Morris, Geoffrey P. ^{[1
]}

Borevitz, Justin O. ^{[1
]}

机构：

[1] Univ Chicago, Dept Ecol & Evolut, Chicago, IL 60637 USA

来源：

GENOME BIOLOGY | 2011年 / 12卷 / 10期

关键词：

FLOWERING TIME ADAPTATION; NATURAL ALLELIC VARIATION; ARABIDOPSIS-THALIANA; GENETIC ARCHITECTURE; MAPPING POPULATION; LINKAGE DISEQUILIBRIUM; LATITUDINAL CLINE; MODEL SYSTEM; MAIZE GENOME; TRAITS;

D O I：

10.1186/gb-2011-12-10-232

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Genome-wide association studies (GWAS) have been even more successful in plants than in humans. Mapping approaches can be extended to dissect adaptive genetic variation from structured background variation in an ecological context.

引用

页数：8

共 59 条

[1] Multiplexed shotgun genotyping for rapid and efficient genetic mapping [J].

Andolfatto, Peter ;

Davison, Dan ;

Erezyilmaz, Deniz ;

Hu, Tina T. ;

Mast, Joshua ;

Sunayama-Morita, Tomoko ;

Stern, David L. .

GENOME RESEARCH, 2011, 21 (04) :610-617

[2]

[Anonymous], 1001 genomes: A catalog of Arabidopsis thaliana genetic variation

[3] Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines [J].

Atwell, Susanna ;

Huang, Yu S. ;

Vilhjalmsson, Bjarni J. ;

Willems, Glenda ;

Horton, Matthew ;

Li, Yan ;

Meng, Dazhe ;

Platt, Alexander ;

Tarone, Aaron M. ;

Hu, Tina T. ;

Jiang, Rong ;

Muliyati, N. Wayan ;

Zhang, Xu ;

Amer, Muhammad Ali ;

Baxter, Ivan ;

Brachi, Benjamin ;

Chory, Joanne ;

Dean, Caroline ;

Debieu, Marilyne ;

de Meaux, Juliette ;

Ecker, Joseph R. ;

Faure, Nathalie ;

Kniskern, Joel M. ;

Jones, Jonathan D. G. ;

Michael, Todd ;

Nemri, Adnane ;

Roux, Fabrice ;

Salt, David E. ;

Tang, Chunlao ;

Todesco, Marco ;

Traw, M. Brian ;

Weigel, Detlef ;

Marjoram, Paul ;

Borevitz, Justin O. ;

Bergelson, Joy ;

Nordborg, Magnus .

NATURE, 2010, 465 (7298) :627-631

[4] Towards identifying genes underlying ecologically relevant traits in Arabidopsis thaliana [J].

Bergelson, Joy ;

Roux, Fabrice .

NATURE REVIEWS GENETICS, 2010, 11 (12) :867-879

[5] The impact of genomics on the study of natural variation in Arabidopsis [J].

Borevitz, JO ;

Nordborg, M .

PLANT PHYSIOLOGY, 2003, 132 (02) :718-725

[6] Linkage and Association Mapping of Arabidopsis thaliana Flowering Time in Nature [J].

Brachi, Benjamin ;

Faure, Nathalie ;

Horton, Matt ;

Flahauw, Emilie ;

Vazquez, Adeline ;

Nordborg, Magnus ;

Bergelson, Joy ;

Cuguen, Joel ;

Roux, Fabrice .

PLOS GENETICS, 2010, 6 (05) :40

[7] The Genetic Architecture of Maize Flowering Time [J].

Buckler, Edward S. ;

Holland, James B. ;

Bradbury, Peter J. ;

Acharya, Charlotte B. ;

Brown, Patrick J. ;

Browne, Chris ;

Ersoz, Elhan ;

Flint-Garcia, Sherry ;

Garcia, Arturo ;

Glaubitz, Jeffrey C. ;

Goodman, Major M. ;

Harjes, Carlos ;

Guill, Kate ;

Kroon, Dallas E. ;

Larsson, Sara ;

Lepak, Nicholas K. ;

Li, Huihui ;

Mitchell, Sharon E. ;

Pressoir, Gael ;

Peiffer, Jason A. ;

Rosas, Marco Oropeza ;

Rocheford, Torbert R. ;

Cinta Romay, M. ;

Romero, Susan ;

Salvo, Stella ;

Sanchez Villeda, Hector ;

da Silva, H. Sofia ;

Sun, Qi ;

Tian, Feng ;

Upadyayula, Narasimham ;

Ware, Doreen ;

Yates, Heather ;

Yu, Jianming ;

Zhang, Zhiwu ;

Kresovich, Stephen ;

McMullen, Michael D. .

SCIENCE, 2009, 325 (5941) :714-718

[8] Key impact of Vgt1 on flowering time adaptation in maize:: Evidence from association mapping and ecogeographical information [J].

Ducrocq, Sbastien ;

Madur, Delphine ;

Veyrieras, Jean-Baptiste ;

Camus-Kulandaivelu, Letizia ;

Kloiber-Maitz, Monika ;

Presterl, Thomas ;

Ouzunova, Milena ;

Manicacci, Domenica ;

Charcosset, Alain .

GENETICS, 2008, 178 (04) :2433-2437

[9] VIEWPOINT Missing heritability and strategies for finding the underlying causes of complex disease [J].

Eichler, Evan E. ;

Flint, Jonathan ;

Gibson, Greg ;

Kong, Augustine ;

Leal, Suzanne M. ;

Moore, Jason H. ;

Nadeau, Joseph H. .

NATURE REVIEWS GENETICS, 2010, 11 (06) :446-450

[10] A Robust, Simple Genotyping-by-Sequencing (GBS) Approach for High Diversity Species [J].

Elshire, Robert J. ;

Glaubitz, Jeffrey C. ;

Sun, Qi ;

Poland, Jesse A. ;

Kawamoto, Ken ;

Buckler, Edward S. ;

Mitchell, Sharon E. .

PLOS ONE, 2011, 6 (05)

← 1 2 3 4 5 6 →