Guidelines for the communication of Biomonitoring Equivalents: Report from the Biomonitoring Equivalents Expert Workshop

被引:75
作者
LaKind, Judy S. [2 ]
Aylward, Lesa L. [3 ]
Brunk, Conrad [4 ]
DiZio, Stephen [5 ]
Dourson, Michael [6 ]
Goldstein, Daniel A. [7 ]
Kilpatrick, Michael E. [8 ]
Krewski, Daniel [9 ]
Bartels, Michael J. [10 ]
Barton, Hugh A. [11 ]
Boogaard, Peter J. [12 ]
Lipscomb, John [13 ]
Krishnan, Kannan [14 ]
Nordberg, Monica [15 ]
Okino, Miles [16 ]
Tan, Yu-Mei [17 ]
Viau, Claude [14 ]
Yager, Janice W. [18 ]
Hays, Sean M. [1 ]
机构
[1] Summit Toxicol LLP, Lyons, CO 80540 USA
[2] LaKind Associates LLC, Catonsville, MD 21228 USA
[3] Summit Toxicol LLP, Falls Church, VA 22044 USA
[4] Univ Victoria, Ctr Studies Relig & Soc, Victoria, BC V8W 2Y2, Canada
[5] Interstate Technol &Regulatory Council, Sacramento, CA 95826 USA
[6] Toxicol Excellence Risk Assessment, Cincinnati, OH 45211 USA
[7] Monsanto Co, St Louis, MO 63167 USA
[8] US Dept Def, Force Hlth Protect & Readiness Programs, Falls Church, VA 22041 USA
[9] Univ Ottawa, Inst Populat Hlth, R Samuel McLaughlin Ctr Populat Hlth Risk Assessm, Ottawa, ON K1N 6N5, Canada
[10] Dow Chem Co USA, Toxicol Res Lab, Midland, MI 48674 USA
[11] US EPA, Natl Ctr Computat Toxicol, Res Triangle Pk, NC 27711 USA
[12] Shell Int, Shell Hlth, NL-2501 AN The Hague, Netherlands
[13] US EPA, Cincinnati, OH 45268 USA
[14] Univ Montreal, Dept Sante Environm & Sante Travail, Montreal, PQ H3T 1A8, Canada
[15] Karolinska Inst, Inst Environm Med, SE-17177 Stockholm, Sweden
[16] US EPA, EDRB, Las Vegas, NV 89193 USA
[17] Hamner Inst Hlth Sci, Res Triangle Pk, NC 27709 USA
[18] Univ New Mexico, Dept Internal Med, Div Epidemiol, Albuquerque, NM 87131 USA
关键词
biomonitoring; Biomonitoring Equivalents; risk communication; BEs; transparency; exposure guidance values;
D O I
10.1016/j.yrtph.2008.05.007
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Biomonitoring Equivalents (BEs) are screening tools for interpreting biomonitoring data. However, the development of BEs brings to the public a relatively novel concept in the field of health risk assessment and presents new challenges for environmental risk communication. This paper provides guidance on methods for conveying information to the general public, the health care community, regulators and other interested parties regarding how chemical-specific BEs are derived, what they mean in terms of health, and the challenges and questions related to interpretation and communication of biomonitoring data. Key communication issues include: (i) developing a definition of the BE that accurately captures the BE concept in lay terms, (ii) how to compare population biomonitoring data to BEs, (iii) interpreting biomonitoring data that exceed BEs for a specific chemical, (iv) how to best describe the confidence in chemical-specific BEs, and (v) key requirements for effective communication with health care professionals. While the risk communication literature specific to biomonitoring is sparse, many of the concepts developed for traditional risk assessments apply, including transparency and discussions of confidence and uncertainty. Communication of BEs will require outreach, education, and development of communication materials specific to several audiences including the lay public and health care providers. (c) 2008 Elsevier Inc, All rights reserved.
引用
收藏
页码:S16 / S26
页数:11
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