Estimation in multitype epidemics

被引:21
作者
Britton, T [1 ]
机构
[1] La Trobe Univ, Bundoora, Vic 3083, Australia
关键词
consistent estimator; counting processes; estimating equations; martingales; multitype epidemics; susceptibility and infectivity;
D O I
10.1111/1467-9868.00147
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
A multitype epidemic model is analysed assuming proportionate mixing between types. Estimation procedures for the susceptibilities and infectivities are derived for three sets of data: complete data, meaning that the whole epidemic process is observed continuously; the removal processes are observed continuously; only the final state is observed. Under the assumption of a major outbreak in a population of size n it is shown that, for all three data sets, the susceptibility estimators are always efficient, i.e. consistent with a root n rate of convergence. The infectivity estimators are 'in most cases' respectively efficient, efficient and unidentifiable. However, if some susceptibilities are equal then the corresponding infectivity estimators are respectively barely consistent (root log(n) rate of convergence), not consistent and unidentifiable. The estimators are applied to simulated data.
引用
收藏
页码:663 / 679
页数:17
相关论文
共 8 条