Impact of empirical-therapy selection on outcomes of intravenous drug users with infective endocarditis caused by methicillin-susceptible Staphylococcus aureus

被引：81

作者：

Lodise, Thomas P., Jr.

McKinnon, Peggy S.

Levine, Donald P.

Rybak, Michael J.

机构：

[1] Albany Coll Pharm, Albany, NY 12208 USA

[2] Barnes Jewish Hosp, St Louis, MO 63110 USA

[3] Wayne State Univ, Sch Med, Detroit, MI USA

[4] Detroit Receiving Hosp & Univ Hlth Ctr, Detroit, MI USA

[5] Univ Hlth Ctr, Detroit, MI USA

[6] Wayne State Univ, Coll Pharm & Hlth Sci, Anti Infect Lab, Detroit, MI USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 10期

关键词：

D O I：

10.1128/AAC.00101-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

This study compares beta-lactam and vancomycin among intravenous drug users with infective endocarditis caused by methicillin-susceptible Staphylococcus aureus. Patients who received vancomycin had higher infection-related mortality, even if they were switched to beta-lactam once culture results became available; this relationship persisted after logistic regression analysis controlling for clinical characteristics.

引用

收藏

页码：3731 / 3733

页数：3

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