Surface-nucleated assembly of fibrillar extracellular matrices

被引：17

作者：

Capadona, JR

Petrie, TA

Fears, KP

Latour, RA

Collard, DM

García, ASJ ^{[1
]}

机构：

[1] Georgia Inst Technol, Petit Inst Bioengn & Biosci, Atlanta, GA 30332 USA

[2] Georgia Inst Technol, George W Woodruff Sch Mech Engn, Atlanta, GA 30332 USA

[3] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA

[4] Clemson Univ, Dept Bioengn, Clemson, SC 29634 USA

来源：

ADVANCED MATERIALS | 2005年 / 17卷 / 21期

关键词：

D O I：

10.1002/adma.200500959

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthetic surfaces, presenting a covalently immobilized oligopeptide sequence (FN13) from the self-assembly domain of fibronectin (FN), nucleate and template the assembly of robust fibrillar extracellular matrices. These matrices contain fibronectin and type I collagen (COL), as shown in the Figure, and exhibit increased cell-proliferation rates.

引用

收藏

页码：2604 / +

页数：6

相关论文

共 19 条

[1] Fibronectin matrix regulates activation of Rho and Cdc42 GTPases and cell cycle progression [J].

Bourdoulous, S ;

Orend, G ;

MacKenna, DA ;

Pasqualini, R ;

Ruoslahti, E .

JOURNAL OF CELL BIOLOGY, 1998, 143 (01) :267-276

[2] Matrix assembly induction and cell migration and invasion inhibition by a 13-amino acid fibronectin peptide [J].

Colombi, M ;

Zoppi, N ;

De Petro, G ;

Marchina, E ;

Gardella, R ;

Tavian, D ;

Ferraboli, S ;

Barlati, S .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (16) :14346-14355

[3]

Danen EHJ, 2003, J PATHOL, V200, P471, DOI 10.1002/path.1416

[4] Fibronectin matrix composition and organization can regulate cell migration during amphibian development [J].

Darribère, T ;

Schwarzbauer, JE .

MECHANISMS OF DEVELOPMENT, 2000, 92 (02) :239-250

[5] Integrin and ECM functions - roles in vertebrate development [J].

De Arcangelis, A ;

Georges-Labouesse, E .

TRENDS IN GENETICS, 2000, 16 (09) :389-395

[6] FIBRONECTIN MOLECULE VISUALIZED IN ELECTRON-MICROSCOPY - A LONG, THIN, FLEXIBLE STRAND [J].

ERICKSON, HP ;

CARRELL, N ;

MCDONAGH, J .

JOURNAL OF CELL BIOLOGY, 1981, 91 (03) :673-678

[7] Micropatterned surfaces to engineer focal adhesions for analysis of cell adhesion strengthening [J].

Gallant, ND ;

Capadona, JR ;

Frazier, AB ;

Collard, DM ;

García, AJ .

LANGMUIR, 2002, 18 (14) :5579-5584

[8]

INGHAM KC, 1988, J BIOL CHEM, V263, P4624

[9] A strategy for the generation of surfaces presenting ligands for studies of binding based on an active ester as a common reactive intermediate: A surface plasmon resonance study [J].

Lahiri, J ;

Isaacs, L ;

Tien, J ;

Whitesides, GM .

ANALYTICAL CHEMISTRY, 1999, 71 (04) :777-790

[10] Designing materials for biology and medicine [J].

Langer, R ;

Tirrell, DA .

NATURE, 2004, 428 (6982) :487-492