Chronic myeloid leukemia CD34+cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5) P3 and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors;: effects reversed by imatinib

被引：5

作者：

Hamzah, HG

Pierce, A

Stewart, WA

Downes, CP

Gray, A

Irvine, A

Spooncer, E

Whetton, AD

机构：

[1] Univ Manchester, Fac Med, Christie Hosp, Manchester M20 9BX, Lancs, England

[2] Manchester Royal Infirm, Dept Clin Hematol, Manchester M13 9WL, Lancs, England

[3] Univ Dundee, Sch Life Sci, Dundee, Scotland

[4] Belfast City Hosp, Dept Hematol, Belfast BT9 7AD, Antrim, North Ireland

来源：

LEUKEMIA | 2005年 / 19卷 / 10期

关键词：

D O I：

10.1038/sj.leu.2403919

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1851 / 1853

页数：4

共 6 条

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[5] JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis
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