Vitamin E and atherosclerosis: Beyond prevention of LDL oxidation

被引：55

作者：

Meydani, M ^{[1
]}

机构：

[1] Tufts Univ, Vasc Biol Lab, USDA, Jean Mayer Human Nutr Res Ctr Aging, Boston, MA 02111 USA

来源：

JOURNAL OF NUTRITION | 2001年 / 131卷 / 02期

关键词：

alpha-tocopherol; cardiovascular disease; atherosclerosis; molecular mechanism;

D O I：

10.1093/jn/131.2.366S

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Atherosclerosis is a chronic inflammatory disease of the arterial wall. Observational and experimental studies indicate that dietary vitamin E supplementation is associated with reduced risk of atherosclerosis. Evidence indicates that vitamin E, in addition to inhibition of oxidative modification of LDL, may inhibit atherogenesis through several other mechanisms at the molecular and cellular levels, which also include its nonantioxidant functions.

引用

页码：366S / 368S

页数：3

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