Extra-CNS metastasis from glioblastoma: a rare clinical entity

被引：20

作者：

Awan, Musaddiq ^{[1
]}

Liu, Stanley ^{[2
]}

Sahgal, Arjun ^{[2
]}

Das, Sunit ^{[3
]}

Chao, Samuel T. ^{[4
]}

Chang, Eric L. ^{[5
,6
]}

Knisely, Jonathan P. S. ^{[7
]}

Redmond, Kristin ^{[8
]}

Sohn, Jason W. ^{[1
]}

Machtay, Mitchell ^{[1
,9
]}

Sloan, Andrew E. ^{[9
,10
]}

Mansur, David B. ^{[1
,9
]}

Rogers, Lisa R. ^{[9
,11
]}

Lo, Simon S. ^{[1
,9
]}

机构：

[1] Case Western Reserve Univ, Univ Hosp Seidman Canc Ctr, Dept Radiat Oncol, Cleveland, OH 44106 USA

[2] Univ Toronto, Sunnybrook Hlth Sci Ctr, Dept Radiat Oncol, Toronto, ON, Canada

[3] Univ Toronto, Hosp Sick Children, Labatt Brain Tumour Res Ctr, Div Neurosurg,St Michaels Hosp,Li Ka Shing Knowle, Toronto, ON M5G 1X8, Canada

[4] Cleveland Clin, Rose Ella Burkhardt Brain Tumor & Neurooncol Ctr, Dept Radiat Oncol, Cleveland, OH 44106 USA

[5] Univ So Calif, Keck Sch Med, Dept Radiat Oncol, Los Angeles, CA 90033 USA

[6] Norris Canc Ctr, Los Angeles, CA USA

[7] N Shore Univ Hosp, North Shore Long Isl Jewish Hlth Syst, Dept Radiat Med, Manhasset, NY USA

[8] Johns Hopkins Univ, Dept Radiat Oncol, Baltimore, MD USA

[9] Case Comprehens Canc Ctr, Cleveland, OH USA

[10] Case Western Reserve Univ, Univ Hosp Seidman Canc Ctr, Dept Neurol Surg, Cleveland, OH 44106 USA

[11] Case Western Reserve Univ, Univ Hosp Seidman Canc Ctr, Dept Neurol, Cleveland, OH 44106 USA

来源：

EXPERT REVIEW OF ANTICANCER THERAPY | 2015年 / 15卷 / 05期

关键词：

circulating tumor cells; glioblastoma; gliomas; malignancy in transplant patients; organ transplantation; MULTIPLE EXTRACRANIAL METASTASES; TRANSPLANT TUMOR REGISTRY; SECONDARY GLIOBLASTOMA; ADJUVANT TEMOZOLOMIDE; LYMPH-NODES; STEM-CELLS; BRAIN; MULTIFORME; DONORS; RADIOTHERAPY;

D O I：

10.1586/14737140.2015.1028374

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Extra-CNS metastasis from glioblastoma (ECMGBM) is an emerging but little known clinical entity. We review pre-clinical and translational publications assessing the ability of GBM to spread locally and outside the CNS. Reported cases demonstrating ECMGBM are reviewed providing a summary of presentations for the entity. Special attention is placed on transmission of GBM through organ transplantation. Finally, predictions are made as to the future significance of ECMGBM, especially in the context of better outcomes in CNS GBM.

引用

页码：545 / 552

页数：8

共 60 条

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