Haemodynamic Changes During Early Bereavement: Potential Contribution to Increased Cardiovascular Risk

被引：39

作者：

Buckley, Thomas ^{[1
,2
]}

Mihailidou, Anastasia Susie ^{[1
,3
]}

Bartrop, Roger ^{[3
,4
]}

McKinley, Sharon ^{[5
,6
]}

Ward, Christopher ^{[3
,7
]}

Morel-Kopp, Marie-Christine ^{[3
,7
]}

Spinaze, Monica ^{[1
]}

Tofler, Geoffrey H. ^{[1
,3
]}

机构：

[1] Royal N Shore Hosp, Dept Cardiol, St Leonards, NSW 2065, Australia

[2] Univ Sydney, Sydney Nursing Sch, Sydney, NSW 2006, Australia

[3] Univ Sydney, Sydney Med Sch, Sydney, NSW 2006, Australia

[4] Royal N Shore Hosp, Dept Psychol Med, St Leonards, NSW 2065, Australia

[5] Univ Technol Sydney, Sydney, NSW 2007, Australia

[6] Royal N Shore Hosp, Intens Care Unit, St Leonards, NSW 2065, Australia

[7] Royal N Shore Hosp, Kolling Inst, St Leonards, NSW 2065, Australia

来源：

HEART LUNG AND CIRCULATION | 2011年 / 20卷 / 02期

关键词：

Bereavement; 24-h ambulatory blood pressure; Heart rate; Psychosocial trigger; CORONARY HEART-DISEASE; BLOOD-PRESSURE; FOLLOW-UP; MORTALITY; DEATH; EVENTS; OUTCOMES; SPOUSE;

D O I：

10.1016/j.hlc.2010.10.073

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Background: Bereavement is associated with increased cardiovascular risk, particularly in surviving spouses and parents, however the mechanism is not well understood due to limited studies. The purpose of this study was to evaluate haemodynamic changes (blood pressure (BP) and heart rate (HR)), that may contribute to increased cardiac risk in early bereavement. Methods: We enrolled 80 bereaved individuals and 80 non-bereaved as a reference group. Twenty-four hour ambulatory blood pressure monitoring was performed within two weeks (acute assessment) and at six months following bereavement. Results: Compared to the non-bereaved, the acutely bereaved had higher 24-hour systolic BP (mean (SE) 130.3 (1.5) vs 127.5 (1.4) mm Hg, p = 0.03), higher daytime systolic BP (135.6 (1.5) vs 131.6 (1.4) mm Hg, p = 0.02) and higher daytime systolic load (median % 39.0 vs 29.3, p = 0.02). By six months the BP of the bereaved tended to be lower than acute measures. This difference was significant amongst those not taking BP lowering medications for 24-hour systolic BP (126.5 (2.4) vs 129.7 (2.3) mm Hg, p = 0.04), daytime systolic BP (129.8 (2.1) vs 133.9 (2.0) mm Hg, p = 0.01) and daytime diastolic pressure (76.7 (1.0) vs 78.9 (0.9) mm Hg, p = 0.03). Twenty-four hour heart rate was also higher acutely in the bereaved compared with the reference group (74.0 (1.2) vs 71.7 (0.9) b/min, p = 0.02); at six months heart rate in the bereaved had fallen to non-bereaved levels (70.4 (0.09), p = 0.02). Conclusion: Early bereavement is associated with increased systolic blood pressure and heart rate. These haemodynamic changes may contribute to a time-limited increase in cardiovascular risk. (Heart, Lung and Circulation 2011;20:91-98) 2010 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand. Published by Elsevier Inc. All rights reserved. (Heart, Lung and Circulation 2011;20:91-98) (C) 2010 Australasian Society of Cardiac and Thoracic Surgeons and the Cardiac Society of Australia and New Zealand. Published by Elsevier Inc. All rights reserved.

引用

页码：91 / 98

页数：8

共 36 条

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