Z-trifluoromethyl thioenol ethers, enol ethers, and enamines; Reactivity towards organolithium reagents.

被引：4

作者：

Begue, JP

BonnetDelpon, D

Rock, MH

机构：

[1] BioCIS-CNRS, Centre d'Etudes Pharmaceutiques, F-92296 Châtenay-Malabry, Rue J.B. Clément

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 02期

关键词：

trifluoromethyl-alkenes; -; dienes; -enol ethers; -thio enol ethers; -enamines; organolithium reagents; addition/elimination;

D O I：

10.1016/0040-4039(95)02118-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Trifluoromethyl enol ethers and thioenol ethers conjugated with an unsaturation in the beta-position undergo addition/elimination reactions with organolithium reagents to yield the corresponding trifluoromethyl alkenes while preserving the geometry of the double bond. Trofluoromethyl enamines exhibit a different reactivity towards organolithium reagents with a vinyl anion being formed to preference to addition/elimination products.

引用

页码：171 / 174

页数：4

共 14 条

[1] PREPARATION OF TRIFLUOROMETHYL KETONES AND RELATED FLUORINATED KETONES [J].