Conformational properties and intramolecular weak interactions in substituted dithia[3.3.1]metacyclophanes

Relationship between conformational properties and intramolecular weak interactions of dithia[3.3.1]metacyclophanes carrying a nitro or an amino group on their inner position was studied by H-1 NMR, IR spectra and X-ray structural analyses. It was found out that intramolecular hydrogen-bonding between hydroxy group and one of thr methoxy groups or NH-pi interaction between amino protons and two opposite aromatic rings exerts a major influence on the conformations of these cyclophanes.