Cell cycle: Flies teach an old dogma new tricks

被引:10
作者
Cayirlioglu, P [1 ]
Duronio, RJ
机构
[1] Univ N Carolina, Dept Biol, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA
[3] Univ N Carolina, Program Mol Biol & Biotechnol, Chapel Hill, NC 27599 USA
[4] Univ N Carolina, Curriculum Genet & Mol Biol, Chapel Hill, NC 27599 USA
关键词
D O I
10.1016/S0960-9822(01)00088-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
E2F transcription factors are thought to influence the G1-S cell-cycle transition by controlling expression of genes required for growth and DNA synthesis. But emerging evidence suggests E2F complexes can control the cell cycle independently of transcription by directly regulating DNA replication origin usage during S phase. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:R178 / R181
页数:4
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