Pathogenicity islands: the tip of the iceberg

被引：80

作者：

Hentschel, U ^{[1
]}

Hacker, J ^{[1
]}

机构：

[1] Univ Wurzburg, Inst Mol Infekt Biol, D-97070 Wurzburg, Germany

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 07期

关键词：

pathogenicity islands; genomic islands; horizontal gene transfer; evolution; virulence;

D O I：

10.1016/S1286-4579(01)01410-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Pathogenicity islands represent distinct genetic elements encoding virulence factors of pathogenic bacteria. Pathogenicity islands belong to the class of genomic islands, which are common genetic elements sharing a set of unifying features. Genomic islands have been acquired by horizontal gene transfer. In recent years many different genomic islands have been discovered in a variety of pathogenic as well as non-pathogenic bacteria. Because they promote genetic variability, genomic islands play an important role in microbial evolution. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

页码：545 / 548

页数：4

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