New trends in umbilical cord blood transplantation

被引：120

作者：

Ballen, KK ^{[1
]}

机构：

[1] Massachusetts Gen Hosp, Boston, MA 02114 USA

来源：

BLOOD | 2005年 / 105卷 / 10期

关键词：

D O I：

10.1182/blood-2004-10-4125

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Since the first report of a successful umbilical cord blood transplantation in 1988, there has been great interest in the use of cord blood as an alternative stem cell source to treat cancer and genetic diseases. More than 4000 cord blood transplantations have been performed worldwide. In this review, the scientific rationale for this therapy, as well as related preclinical studies, cord blood banking issues, and ethical concerns, will be addressed. Results of studies in both pediatric and adult transplantation will be discussed. Finally, new indications for cord blood use and emerging technologies will be addressed. (c) 2005 by The American Society of Hematology.

引用

收藏

页码：3786 / 3792

页数：7

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