Identification of Wolbachia-host interacting factors through cytological analysis

被引:72
作者
Tram, U [1 ]
Ferree, PA [1 ]
Sullivan, W [1 ]
机构
[1] Univ Calif Santa Cruz, Dept Mol Cellular & Dev Biol, Santa Cruz, CA 95064 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
Wolbachia; cytoplasmic incompatibility; cell cycle; cytoskeleton;
D O I
10.1016/S1286-4579(03)00192-8
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Manipulation of host reproduction and efficient maternal transmission have facilitated the global spread of Wolbachia through millions of insect species. Cytological studies of the most common Wolbachia-induced phenotype, cytoplasmic incompatibility (CI), demonstrate that Wolbachia induce CI by altering host cell cycle timing. Cytological analyses also suggest that microtubules and motor proteins may play a role in the maternal and somatic transmission of Wolbachia. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:999 / 1011
页数:13
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