Aziridine-2-carboxylic acid mediated asymmetric synthesis of D-erythro- and L-threo-sphingosine from a common precursor

被引：77

作者：

Davis, FA

Reddy, GV

机构：

[1] Department of Chemistry, Temple University, Philadelphia

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 25期

关键词：

D O I：

10.1016/0040-4039(96)00827-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Short, two and three step asymmetric syntheses of L-threo- and D-erythro-sphingosine (-)-6a and (-)-9a, respectively, in 58 and 31 percent overall yield were accomplished via the stereo and regioselective ring opening of N-sulfinylaziridine 2-carboxylic acid 4. Copyright (C) 1996 Elsevier Science Ltd.

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页码：4349 / 4352

页数：4

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