The engine of ABC proteins

被引：13

作者：

Altenberg, GA ^{[1
]}

机构：

[1] Univ Texas, Med Branch, Membrane Prot Lab, Sealy Ctr Struct Biol, Galveston, TX 77555 USA

[2] Univ Texas, Med Branch, Dept Physiol & Biophys, Galveston, TX 77555 USA

来源：

NEWS IN PHYSIOLOGICAL SCIENCES | 2003年 / 18卷

关键词：

D O I：

10.1152/nips.01445.2003

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Proteins that belong to the ATP-binding cassette superfamily span from bacteria to humans and comprise one of the largest protein families. These proteins are characterized by the presence of two nucleotide-binding domains, and recent studies suggest that association and dissociation of these domains is a common basic molecular mechanism of operation that couples ATP binding/hydrolysis to substrate transport across membranes.

引用

页码：191 / 195

页数：5

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