Procalcitonin - a marker of invasive fungal infection?

被引：45

作者：

Dornbusch, HJ ^{[1
]}

Strenger, V

Kerbl, R

Lackner, H

Schwinger, W

Sovinz, P

Urban, C

机构：

[1] Med Univ Graz, Dept Pediat & Adolescence Med, Div Pediat Hematol & Oncol, Graz, Austria

[2] Med Univ Graz, Dept Pediat & Adolescence Med, Div Gen Pediat, Graz, Austria

来源：

SUPPORTIVE CARE IN CANCER | 2005年 / 13卷 / 05期

关键词：

procalcitonin; marker; invasive fungal infection; aspergillosis; candidiasis;

D O I：

10.1007/s00520-004-0721-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Procalcitonin (PCT) has been described as a marker of bacterial sepsis. However, little is known of its diagnostic value in fungal infections. We calculated the sensitivity of PCT for detection of invasive fungal infections (IFI) by analyzing 55 episodes of proven or probable IFI (three in our series, 52 reported in the recent literature). In the early phase of IFI, PCT was elevated in fewer than half of invasive candidiasis episodes and in only one patient (5.3%) with invasive aspergillosis. Due to low sensitivity and specificity, PCT adds little to the diagnosis of IFI.

引用

页码：343 / 346

页数：4

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